Evidence map›Paper›PMID 39275297›Full record

ArticleNutrients2024

Impact of Overweight on Response to Dupilumab Treatment in Chronic Rhinosinusitis with Nasal Polyps.

Michael Habenbacher, Ulrich Moser, Ahmed Abaira, Peter Valentin Tomazic, Peter Kiss, Clemens Holzmeister, Jakob Pock, Katharina Walla, Angelika Lang, Alexandros Andrianakis

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michael HabenbacherDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.
Ulrich MoserDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-2095-3453
Ahmed AbairaDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.
Peter Valentin TomazicDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.
Peter KissDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0001-9187-2063
Clemens HolzmeisterDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.
Jakob PockDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.
Katharina WallaDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.
Angelika LangDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.
Alexandros AndrianakisDepartment of Otorhinolaryngology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-2530-9931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic rhinosinusitis with nasal polyps (CRSwNP) significantly impacts quality of life and often presents therapeutic challenges, with biologics like dupilumab showing promise in managing severe, uncontrolled cases. The aim of this study was to assess the influence of overweight on the effectiveness of dupilumab in patients with uncontrolled CRSwNP. This retrospective study analyzed treatment outcomes of 75 CRSwNP patients receiving dupilumab, categorizing them into underweight/normal-weight (BMI ≤ 24.9 kg/m

Indexed as

Antibodies, Monoclonal, HumanizedBody Mass IndexNasal PolypsOverweightRhinitisSinusitisAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedObesityQuality of LifeRetrospective StudiesAntibodies, Monoclonal, Humanizeddupilumabbiologicchronic rhinosinusitisCRSwNPdupilumabobesityoverweight

Identifiers

PMID39275297
PMCPMC11397523

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.