Evidence map›Paper›PMID 39275254›Full record

SynthesisNutrients2024

Rapid Growth between 0 and 2 Years Old in Healthy Infants Born at Term and Its Relationship with Later Obesity: A Systematic Review and Meta-Analysis of Evidence.

Luz Doñate Carramiñana, Cristina Guillén Sebastián, Iris Iglesia Altaba, Carlos Nagore Gonzalez, Maria Luisa Alvarez Sauras, Sheila García Enguita, Gerardo Rodriguez Martinez

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Body composition at 2 years of age in moderate and late preterm infants.Journal of pediatric gastroenterology and nutrition · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luz Doñate CarramiñanaDepartment of Pediatrics, University of Zaragoza, 50012 Zaragoza, Spain.
Cristina Guillén SebastiánInstituto de Investigación Sanitaria Aragón (IISAragón), 50012 Zaragoza, Spain.
Iris Iglesia AltabaInstituto de Investigación Sanitaria Aragón (IISAragón), 50012 Zaragoza, Spain.ORCID 0000-0002-2219-3646
Carlos Nagore GonzalezInstituto de Investigación Sanitaria Aragón (IISAragón), 50012 Zaragoza, Spain.ORCID 0000-0003-4659-7378
Maria Luisa Alvarez SaurasInstituto de Investigación Sanitaria Aragón (IISAragón), 50012 Zaragoza, Spain.ORCID 0000-0002-1715-962X
Sheila García EnguitaInstituto de Investigación Sanitaria Aragón (IISAragón), 50012 Zaragoza, Spain.
Gerardo Rodriguez MartinezDepartment of Pediatrics, University of Zaragoza, 50012 Zaragoza, Spain.ORCID 0000-0002-7985-9912

Funding

European Union Next Generation EU RD21/0012/0012
6 · The paper itself

Abstract

introductionRapid growth in early childhood has been identified as a possible risk factor for long-term adiposity. However, there is a lack of studies quantifying this phenomenon only in healthy, full-term infants with appropriate birth weight for gestational age. This systematic review and meta-analysis aimed to investigate the association of rapid growth in full-term children up to 2 years of age with adiposity up to 18 years of age. METHODOLOGY: A systematic review of the literature was conducted in PubMed, EMBASE, and Web of Science.

results14 studies were included. We were unable to find strong evidence that rapid growth in early childhood is a risk factor for long-term adiposity. Rapid growth in early childhood was associated with taller heights (standardized mean difference: 0.51 (CI: 0.25-0.77)) and higher body mass index (standardized mean difference: 0.50 (CI: 0.25-0.76)) and a higher risk of overweight under 18 years.

conclusionRapid growth in early childhood in term infants with appropriate birth weight is associated with higher growth, body mass index, and risk of being overweight up to age 18, but further work is needed to identify the associations between early rapid growth and obesity later in adulthood.

Indexed as

Birth WeightChild DevelopmentAdiposityAdolescentBody Mass IndexChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleObesityPediatric ObesityRisk FactorsTerm Birthobesityoverweightpostnatal growthprogrammingrapid weight gain

Identifiers

PMID39275254
PMCPMC11397548

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.