Evidence map›Paper›PMID 39275167›Full record

Trial reportNutrients2024

From Vineyard to Vision: Efficacy of Maltodextrinated Grape Pomace Extract (MaGPE) Nutraceutical Formulation in Patients with Diabetic Retinopathy.

Elisabetta Schiano, Sabrina Vaccaro, Vincenzo Scorcia, Adriano Carnevali, Massimiliano Borselli, Domenico Chisari, Fabrizia Guerra, Fortuna Iannuzzo, Gian Carlo Tenore, Giuseppe Giannaccare and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elisabetta SchianoInventia Biotech-Healthcare Food Research Center s.r.l., Strada Statale Sannitica KM 20.700, 81020 Caserta, Italy.ORCID 0000-0002-8167-0334
Sabrina VaccaroDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-0881-1276
Vincenzo ScorciaDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-6826-7957
Adriano CarnevaliDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Massimiliano BorselliDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-5262-9765
Domenico ChisariDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Fabrizia GuerraInventia Biotech-Healthcare Food Research Center s.r.l., Strada Statale Sannitica KM 20.700, 81020 Caserta, Italy.
Fortuna IannuzzoDepartment of Pharmacy, University of Chieti-Pescara G. D'Annunzio, 66100 Chieti, Italy.ORCID 0000-0001-6340-6698
Gian Carlo TenoreDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-0251-9936
Giuseppe GiannaccareEye Clinic, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-2617-0289
Ettore NovellinoInventia Biotech-Healthcare Food Research Center s.r.l., Strada Statale Sannitica KM 20.700, 81020 Caserta, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances, pharmacological treatments of diabetic retinopathy (DR) do not directly address the underlying oxidative stress. This study evaluates the efficacy of a nutraceutical formulation based on maltodextrinated grape pomace extract (MaGPE), an oxidative stress inhibitor, in managing DR. A 6-month, randomized, placebo-controlled clinical trial involving 99 patients with mild to moderate non-proliferative DR was conducted. The MaGPE group showed improvement in best-corrected visual acuity (BCVA) values at T3 (

Indexed as

Diabetic RetinopathyDietary SupplementsOxidative StressPlant ExtractsPolysaccharidesVisual AcuityVitisAgedAntioxidantsFemaleHumansLipoproteins, LDLMaleMiddle AgedReactive Oxygen SpeciesTreatment OutcomeAntioxidantsLipoproteins, LDLmaltodextrinoxidized low density lipoproteinPlant ExtractsPolysaccharidesReactive Oxygen Speciesdiabetesdiabetic retinopathygrape pomace polyphenolsmacular degenerationnutraceuticalsoxidative stress

Identifiers

PMID39275167
PMCPMC11397461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.