Evidence map›Paper›PMID 39275164›Full record

ArticleNutrients2024

Okinawa-Based Nordic Diet Decreases Plasma Glial Fibrillary Acidic Protein Levels in Type 2 Diabetes Patients.

Dovilė Pocevičiūtė, Malin Wennström, Bodil Ohlsson

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dovilė PocevičiūtėCognitive Disorder Research Unit, Department of Clinical Sciences Malmö, Lund University, 214 28 Malmö, Sweden.ORCID 0009-0001-7400-6339
Malin WennströmCognitive Disorder Research Unit, Department of Clinical Sciences Malmö, Lund University, 214 28 Malmö, Sweden.ORCID 0000-0002-9957-1801
Bodil OhlssonDepartment of Internal Medicine, Lund University, Skåne University Hospital, 214 28 Malmö, Sweden.ORCID 0000-0002-9142-5244

Funding

Åhlén-Stiftelsen 223006Brain Foundation FO2022-0039Crafoord Foundation 20230519Dementia Foundation 2021Development Foundation of Region Skåne 2014/354Dir Albert Påhlsson's Foundation FB2014-0001Greta and Johan Kockska Foundation 2021Olle Engkvists Foundation 194-643
6 · The paper itself

Abstract

Elevated levels of glial fibrillary acidic protein (GFAP) in plasma reflect neuroinflammation and are linked to cognitive decline. Preclinical studies show that dietary change can attenuate astrocyte reactivity and neuroinflammation. In the current study, we investigate if the Okinawa-based Nordic (O-BN) diet alters plasma GFAP levels in patients with Type 2 Diabetes (T2D), a metabolic disorder associated with cognitive disturbances and an increased risk of dementia. Plasma GFAP levels were measured in T2D patients (n = 30) at baseline, after 3 months of the diet, and after a subsequent 4 months of unrestricted diets. The GFAP levels decreased significantly after 3 months of the diet (

Indexed as

Diabetes Mellitus, Type 2Glial Fibrillary Acidic ProteinAgedBiomarkersCytokinesDietFemaleHumansJapanMaleMiddle AgedNeuroinflammatory DiseasesBiomarkersCytokinesGFAP protein, humanGlial Fibrillary Acidic Proteinastrocytecytokinegut–brain axisneuroinflammationplasma

Identifiers

PMID39275164
PMCPMC11396978

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.