Evidence map›Paper›PMID 39275130›Full record

ArticleNutrients2024

Determination of the Protein and Amino Acid Content of Fruit, Vegetables and Starchy Roots for Use in Inherited Metabolic Disorders.

Fiona Boyle, Gary Lynch, Clare M Reynolds, Adam Green, Gemma Parr, Caoimhe Howard, Ina Knerr, Jane Rice

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. The Influence of Pre-Harvest Application ofFoods (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Impact ofFrontiers in nutrition · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fiona BoyleDepartment of Nutrition and Dietetics, National Centre for Inherited Metabolic Disorders, Children's Health Ireland, Temple Street, D01 XD99 Dublin, Ireland.
Gary LynchSchool of Public Health, Physiotherapy and Sports Science, University College Dublin, Belfield, D04 V2P1 Dublin, Ireland.
Clare M ReynoldsSchool of Public Health, Physiotherapy and Sports Science, University College Dublin, Belfield, D04 V2P1 Dublin, Ireland.ORCID 0000-0001-5782-6303
Adam GreenALS Laboratories (UK) Limited, ALS Food and Pharmaceutical, Medcalfe Way, Bridge St., Chatteris PE16 6QZ, UK.
Gemma ParrALS Laboratories (UK) Limited, ALS Food and Pharmaceutical, Medcalfe Way, Bridge St., Chatteris PE16 6QZ, UK.
Caoimhe HowardNational Centre for Inherited Metabolic Disorders, Children's Health Ireland, Temple Street, D01 XD99 Dublin, Ireland.ORCID 0000-0003-4413-7933
Ina KnerrNational Centre for Inherited Metabolic Disorders, Children's Health Ireland, Temple Street, D01 XD99 Dublin, Ireland.ORCID 0000-0002-4015-0658
Jane RiceDepartment of Nutrition and Dietetics, National Centre for Inherited Metabolic Disorders, Children's Health Ireland, Temple Street, D01 XD99 Dublin, Ireland.

Funding

Children's Health Foundation RPAC 19-02-IKChildrens Health Foundation GAP21-86
6 · The paper itself

Abstract

Amino acid (AA)-related inherited metabolic disorders (IMDs) and urea cycle disorders (UCDs) require strict dietary management including foods low in protein such as fruits, vegetables and starchy roots. Despite this recommendation, there are limited data on the AA content of many of these foods. The aim of this study is to describe an analysis of the protein and AA content of a range of fruits, vegetables and starchy roots, specifically focusing on amino acids (AAs) relevant to AA-related IMDs such as phenylalanine (Phe), methionine (Met), leucine (Leu), lysine (Lys) and tyrosine (Tyr). AA analysis was performed using high-performance liquid chromatography (HPLC) on 165 food samples. Protein analysis was also carried out using the Dumas method. Foods were classified as either 'Fruits', 'Dried fruits', 'Cruciferous vegetables', 'Legumes', 'Other vegetables' or 'Starchy roots'. 'Dried fruits' and 'Legumes' had the highest median values of protein, while 'Fruits' and 'Cruciferous vegetables' contained the lowest median results. 'Legumes' contained the highest and 'Fruits' had the lowest median values for all five AAs. Variations were seen in AA content for individual foods. The results presented in this study provide useful data on the protein and AA content of fruits, vegetables and starchy roots which can be used in clinical practice. This further expansion of the current literature will help to improve diet quality and metabolic control among individuals with AA-related IMDs and UCDs.

Indexed as

Amino AcidsDietary ProteinsFruitPlant RootsStarchVegetablesChromatography, High Pressure LiquidHumansMetabolic DiseasesNutritive ValueAmino AcidsDietary ProteinsStarchamino acidsfruitsglutaric aciduria type 1homocystinuriainherited metabolic disordersleucinelysinemaple syrup urine diseasemethioninephenylalaninephenylketonuriaproteinstarchy rootstyrosinaemiatyrosineurea cycle disordersvegetables

Identifiers

PMID39275130
PMCPMC11397706

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.