Evidence map›Paper›PMID 39275092›Full record

ArticleMolecules (Basel, Switzerland)2024

Design and Synthesis of an Azo Reductase Responsive Flavonol-Indomethacin Hybrid Used for the Diagnosis and Treatment of Colitis.

Yaqin Gu, Rui Yang, Jine Chen, Yu Fan, Wenna Xie, Hongyan Wu, Jinfeng Ding

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaqin GuSchool of Pharmacy, Jiangsu Vocational College of Medicine, Yancheng 224005, China.
Rui YangSchool of Pharmacy, Jiangsu Vocational College of Medicine, Yancheng 224005, China.
Jine ChenSchool of Pharmacy, Jiangsu Vocational College of Medicine, Yancheng 224005, China.
Yu FanSchool of Pharmacy, Nantong University, Nantong 226019, China.
Wenna XieSchool of Pharmacy, Jiangsu Vocational College of Medicine, Yancheng 224005, China.
Hongyan WuSchool of Pharmacy, Jiangsu Vocational College of Medicine, Yancheng 224005, China.
Jinfeng DingSchool of Pharmacy, Jiangsu Vocational College of Medicine, Yancheng 224005, China.

Funding

Jiangsu Higher Education Institution Innovative Research Team For Science and Technology 2023The"Qinglan Project"of Jiangsu College 2024
6 · The paper itself

Abstract

Human intestinal bacteria are the primary producers of azo reductase, and the content of azo reductase is closely associated with various intestinal diseases, including ulcerative colitis (UC). The rapid detection of changes in azo reductase levels is crucial for diagnosing and promptly intervening in UC. In this study, a therapeutic agent,

Indexed as

FlavonolsIndomethacinAnimalsAnti-Inflammatory AgentsColitis, UlcerativeDisease Models, AnimalDrug DesignHumansMiceNADH, NADPH OxidoreductasesNitroreductasesAnti-Inflammatory AgentsazoreductaseFlavonolsIndomethacinNADH, NADPH OxidoreductasesNitroreductasesazoreductasediagnosisflavonolsindomethacintreatmentulcerative colitis

Identifiers

PMID39275092
PMCPMC11397019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.