Evidence map›Paper›PMID 39274758›Full record

ArticleMaterials (Basel, Switzerland)2024

Antibacterial Dental Adhesive Containing Cetylpyridinium Chloride Montmorillonite.

Yohei Okazaki, Kiichi Nakamori, Chenmin Yao, Mohammed H Ahmed, Benjamin Mercelis, Noriyuki Nagaoka, Yukinori Maruo, Yasuhiro Yoshida, Yasuhiko Abe, Bart Van Meerbeek and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yohei OkazakiDepartment of Oral Health Sciences, BIOMAT, KU Leuven, 3000 Leuven, Belgium.
Kiichi NakamoriDepartment of Advanced Prosthodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Chenmin YaoDepartment of Oral Health Sciences, BIOMAT, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-7673-4295
Mohammed H AhmedDepartment of Oral Health Sciences, BIOMAT, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-4342-7744
Benjamin MercelisDepartment of Oral Health Sciences, BIOMAT, KU Leuven, 3000 Leuven, Belgium.
Noriyuki NagaokaAdvanced Research Center for Oral and Craniofacial Science, Okayama University Dental School, Okayama 700-8558, Japan.
Yukinori MaruoDepartment of Prosthodontics, Okayama University, Okayama 700-8558, Japan.
Yasuhiro YoshidaDepartment of Biomaterials and Bioengineering, Faculty of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan.
Yasuhiko AbeDepartment of Advanced Prosthodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
Bart Van MeerbeekDepartment of Oral Health Sciences, BIOMAT, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-4097-5836
Kumiko YoshiharaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu 761-0395, Japan.ORCID 0000-0002-3483-6012

Funding

JSPS Kakenhi 23K18597, 23K09276, 23K16089.
6 · The paper itself

Abstract

Oral bacteria cause tooth caries and periodontal disease. Much research is being conducted to prevent both major oral diseases by rendering dental materials' antimicrobial potential. However, such antimicrobial materials are regarded as 'combination' products and face high hurdles for regulatory approval. We loaded inorganic montmorillonite with the antimicrobial agent cetylpyridinium chloride, referred to below as 'CPC-Mont'. CPC-Mont particles in a 1, 3 and 5 wt% concentration were added to the considered gold-standard self-etch adhesive Clearfil SE Bond 2 ('CSE2'; Kuraray Noritake) to render its antibacterial potential (CSE2 without CPC-Mont served as control). Besides measuring (immediate) bonding effectiveness and (aged) bond durability to dentin, the antibacterial activity against

Indexed as

antibacterial agentdegree of conversiondental adhesivedentinmicro tensile bond strengthscanning microscopy

Identifiers

PMID39274758
PMCPMC11395986

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.