ReviewJournal of clinical medicine2024
Adenomyosis: An Update Concerning Diagnosis, Treatment, and Fertility.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07065539 (The Impact of Duration of Gonadotropin-Releasing Hormone Agonist Pretreatment and Letrozole Supplementation on Pregnancy Outcomes in Frozen-Thawed Embryo Transfer Cycles for Patients With Adenomyosis), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Duration of Gonadotropin-Releasing Hormone Agonist Pretreatment and Letrozole Supplementation on Pregnancy Outcomes in Frozen-Thawed Embryo Transfer Cycles for Patients With Adenomyosis: A 2 by 2 Factorial Multicenter, Randomized Controlled Trial
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-Coding RNAs (microRNAs, lncRNAs, circRNAs) in Adenomyosis: A Systematic Review of Mechanistic and Translational Evidence.International journal of molecular sciences · 2025Pooled it
- Treatment selection for adenomyosis based on imaging findings and patient characteristics.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Review
- Adenomyosis, Infertility and Maternal-Fetal Outcomes: Diagnostic and Therapeutic Strategies Across Disease Phenotype-A Narrative Review.Journal of clinical medicine · 2026Review
- Transvaginal Sonographic Features of Diffuse Adenomyosis and Associated Symptoms in 18-30-Year-Old Nulligravid Women Without Endometriosis: Is Our Diagnosis Still Valid 10 Years Later? A Re-Evaluation of Previous Results.Journal of clinical medicine · 2026Article
- Subtype-specific analysis of factors associated with assisted reproductive technology indication and live birth in patients with adenomyosis: a retrospective study.Archives of gynecology and obstetrics · 2026Article
- Screening of a Novel SynonymousBiomedicines · 2026Article
- Total Vaginal Hysterectomy Can Provide a Feasible Surgical Approach for Benign Conditions: A Study on Enlarged Diffuse Uterine Adenomyosis from Romania.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Navigating complexity: review and updates of endometriosis and adenomyosis imaging.The British journal of radiology · 2026Review
- Long-term efficacy of uterine artery embolization for adenomyosis and analysis of prognostic factors: a cohort study.BMC women's health · 2026Article
- Endometriosis and Fertility: A Practical Guide: Results of the Working Group of the Weissensee 2025 Workshop of the Scientific Endometriosis Foundation.Geburtshilfe und Frauenheilkunde · 2026Article
- Ectopic Pregnancy with a Normally Located Levonorgestrel-Releasing Intrauterine System in a Woman with Adenomyosis: Case Report and Literature Review.Journal of clinical medicine · 2025Review
- Expert transvaginal ultrasound is determinant for diagnosing pelvic conditions after recurrent implantation failure in IVF.European journal of obstetrics & gynecology and reproductive biology: X · 2025Article
- Endometriosis and infertility: pathophysiology, treatment strategies, and reproductive outcomes.Archives of gynecology and obstetrics · 2025Review
- The present adenomyosis treatment status in Luzhou, China: a small scope observational cross-sectional survey.BMC women's health · 2025Observational
- Comparison and correlations between findings of hysteroscopy and vaginal color Doppler ultrasonography for detection of uterine abnormalities in patients with recurrent implantation failure.Open medicine (Warsaw, Poland) · 2025Article
- A newly identified allelic mutation c.110C>T in theGynecology and pelvic medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review article aims to summarize current tools used in the diagnosis of adenomyosis with relative pharmacological and surgical treatment and to clarify the relative association between adenomyosis and infertility, considering the importance of an accurate diagnosis of this heterogeneous disease. Among different reported concepts, direction invagination of gland cells from the basalis endometrium deep into the myometrium is the most widely accepted opinion on the development of adenomyosis. Adenomyosis has been increasingly identified in young women with pain, AUB, infertility, or no symptoms by using imaging techniques such as transvaginal ultrasound and magnetic resonance. Furthermore, adenomyosis often coexists with other gynecological conditions, such as endometriosis and uterine fibroids, increasing the heterogeneity of available data. However, there is no agreement on the definition and classification of adenomyotic lesions from both the histopathology and the imaging points of view, and diagnosis remains difficult and unclear. A standard, universally accepted classification system needs to be implemented to improve our understanding and inform precise diagnosis of the type of adenomyosis. This could be the key to designing RCT studies and evaluating the impact of adenomyosis on quality of life in terms of menstrual symptoms, fertility, and pregnancy outcome, given the high risk of miscarriage and obstetric complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.