Evidence map›Paper›PMID 39274360›Full record

ArticleJournal of clinical medicine2024

Clinical Trial: A Pragmatic Randomised Controlled Study to Assess the Effectiveness of Two Patient Management Strategies in Mild to Moderate Ulcerative Colitis-The OPTIMISE Study.

Silvio Danese, Gionata Fiorino, Eric Vicaut, Kristine Paridaens, Asiya Ugur, Brian Clark, Tomas Vanasek, David Stepek, Ferdinando D'Amico, Rachel West and 10 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04340895 (Pragmatic Randomized Controlled Study to Assess the Effectiveness of Two Patient Management Strategies in Mild to Moderate Ulcerative Colitis), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04340895 nacompletednot on this map

Pragmatic Randomized Controlled Study to Assess the Effectiveness of Two Patient Management Strategies in Mild to Moderate Ulcerative Colitis

TypeinterventionalSponsorFerring PharmaceuticalsRan2019 to 2023Enrolled250ConditionsMild-to-moderate Ulcerative ColitisArmsFaecal Calprotectin Home Test, PRO-2 Scoring
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. [New treatment targets for inflammatory bowel disease?]Innere Medizin (Heidelberg, Germany) · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Silvio DaneseDepartment of Gastroenterology and Digestive Endoscopy, San Raffaele Hospital, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0001-7341-1351
Gionata FiorinoIBD Unit, Department of Gastroenterology and Digestive Endoscopy, San Camillo-Forlanini Hospital, 00152 Rome, Italy.ORCID 0000-0001-5623-2968
Eric VicautClinical Trial Unit, Hospital Lariboisière APHP, 75010 Paris, France.ORCID 0000-0001-6303-8557
Kristine ParidaensFerring International Center S.A, 1162 Saint-Prex, Switzerland.ORCID 0000-0001-6865-5415
Asiya UgurFerring Pharmaceuticals A/S, 2770 Kastrup, Denmark.ORCID 0009-0004-5705-8462
Brian ClarkFerring Pharmaceuticals A/S, 2770 Kastrup, Denmark.
Tomas VanasekHepato-Gastroenterologie HK, s.r.o., 50012 Hradec Králové, Czech Republic.
David StepekInternal Department, Military Hospital Brno, 61500 Brno, Czech Republic.
Ferdinando D'AmicoDepartment of Gastroenterology and Digestive Endoscopy, San Raffaele Hospital, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0002-8591-6995
Rachel WestDepartment of Gastroenterology and Hepatology, Franciscus Gasthuis & Vlietland, 3045 PM Rotterdam, The Netherlands.
Lennard P L GilissenDepartment of Gastroenterology and Hepatology, Catharina Hospital Eindhoven, 5623 EJ Eindhoven, The Netherlands.
Maria Wisniewska JarosinkaDepartment of Gastroenterology, Medical University of Lodz, 92-213 Lodz, Poland.
Piotr DrobinskiCentrum Medyczne Lukamed in Chojnice, 89-600 Chojnice, Poland.
Grzegorz FronikMelita Medical-Centrum Proktologii, Onkologii i Chorób Jelit, 50-449 Wrocław, Poland.
Mirosław FicPolish Society of Gastroenterology, 58-521 Jezów Sudecki, Poland.
Michał WalczakInstitute of Human Genetics, Polish Academy of Sciences, 61-772 Poznan, Poland.
Maciej KowalskiDepartment of Gastroenterology, Centrum Diagnostyczno-Lecznicze Barska, 87-806 Włocławek, Poland.
Bartosz KorczowskiInstitute of Medical Sciences, Medical College, University of Rzeszów, 35-310 Rzeszów, Poland.ORCID 0000-0003-1626-1283
Michal WiatrOśrodek Badań Klinicznych CLINSANTE S.C. Ewa Galczak-Nowak Małgorzata Trzaska, Chałubińskiego, 85-004 Bydgoszcz, Poland.
Laurent Peyrin-BirouletDepartment of Gastroenterology and Inserm NGERE U1256, University Hospital of Nancy, University of Lorraine, 54000 Vandoeuvre-lès-Nancy, France.

Funding

Ferring Pharmaceuticals NA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

faecal calprotectininflammatory bowel diseasetight monitoringtreat-to-targetulcerative colitis

Identifiers

PMID39274360
PMCPMC11395821

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.