Evidence map›Paper›PMID 39274196›Full record

ArticleJournal of clinical medicine2024

Pharmacokinetics of Efmoroctocog alfa by Two-Compartment Model Highlights Hemophilia A Patients with Biphasic Decay, Long Mean Residence Time, and Beta Half-Life.

Massimo Morfini, Flora Peyvandi, Maria Elisa Mancuso, Emanuela Marchesini, Annarita Tagliaferri, Roberta Gualtierotti, Giancarlo Castaman, Berardino Pollio, Cristina Santoro, Luisa Banov and 7 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Massimo MorfiniItalian Association of Hemophilia Centers (AICE), I 20120 Milan, Italy.ORCID 0000-0001-6565-4943
Flora PeyvandiDepartment of Pathophysiology and Transplantation, University of Milan, Fondazione IRCSS Ca' Granda Maggiore Hospital, "Angelo Bianchi Bonomi", I 20120 Milan, Italy.ORCID 0000-0001-7423-9864
Maria Elisa MancusoCenter for Thrombosis and Hemorrhagic Diseases, IRCCS " Humanitas Research Hospital", Rozzano, I 20142 Milan, Italy.ORCID 0000-0002-7113-4028
Emanuela MarchesiniHemophilia Centre, Internal and Cardiovascular Medicine, "Santa Maria della Misericordia" University Hospital, I 06100 Perugia, Italy.
Annarita TagliaferriRegional Reference Centre for Inherited Bleeding Disorders, University Hospital of Parma, I 43100 Parma, Italy.ORCID 0000-0003-3529-6334
Roberta GualtierottiDepartment of Pathophysiology and Transplantation, University of Milan, Fondazione IRCSS Ca' Granda Maggiore Hospital, "Angelo Bianchi Bonomi", I 20120 Milan, Italy.ORCID 0000-0001-6465-7624
Giancarlo CastamanDepartment of Oncology, Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, I 50139 Florence, Italy.ORCID 0000-0003-4973-1317
Berardino PollioRegional Reference Centre for Inherited Bleeding and Thrombotic Disorders, Transfusion Medicine, "Regina Margherita" Children Hospital, I 10100 Turin, Italy.
Cristina SantoroDepartment of Hematology, University Hospital Policlinico "Umberto I", I 00100 Rome, Italy.
Luisa BanovRegional Reference Centre for Hemorrhagic Diseases, IRCCS Istituto "Giannina Gaslini", I 16100 Genoa, Italy.
Mariasanta NapolitanoHematology Unit, Thrombosis and Hemostasis Reference Regional Centre, University of Palermo, I 90100 Palermo, Italy.ORCID 0000-0001-8934-2936
Paola Stefania PretiDepartment of Internal Medicine and Therapeutics, University of Pavia, I 27100 Pavia, Italy.
Rita Carlotta SantoroRegional Reference Centre for Hemophilia and Coagulation Diseases, Azienda Ospedaliera Pugliese "Ciaccio", I 88100 Catanzaro, Italy.ORCID 0000-0002-5081-8201
Antonio CoppolaRegional Reference Centre for Inherited Bleeding Disorders, University Hospital of Parma, I 43100 Parma, Italy.ORCID 0000-0003-3697-706X
Silvia LinariDepartment of Oncology, Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, I 50139 Florence, Italy.ORCID 0000-0002-5849-7377
Elena SantagostinoSOBI, SE-11276 Stockholm, Sweden.
Francesco BernardiDepartment of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, I 44121 Ferrara, Italy.ORCID 0000-0003-0305-2212

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Efmoroctocog alfaHemophilia Anon-compartmental analysisone compartment modelpharmacokineticsrFVIIIFctwo compartment model

Identifiers

PMID39274196
PMCPMC11396525

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.