Evidence map›Paper›PMID 39274152›Full record

ArticlePolymers2024

Early Biological Response to Poly(ε-Caprolactone)/Alumina-Toughened Zirconia Composites Obtained by 3D Printing for Peri-Implant Application.

Riccardo Pedraza, Alessandro Mosca Balma, Ilaria Roato, Clarissa Orrico, Tullio Genova, Giacomo Baima, Giovanni Nicolao Berta, Andrea Giura, Luigi Ribotta, Donatella Duraccio and 2 more

Abstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Riccardo PedrazaBone and Dental Bioengineering Laboratory, CIR Dental School, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0009-0009-2955-4246
Alessandro Mosca BalmaBone and Dental Bioengineering Laboratory, CIR Dental School, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-8095-2524
Ilaria RoatoBone and Dental Bioengineering Laboratory, CIR Dental School, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-3029-4743
Clarissa OrricoBone and Dental Bioengineering Laboratory, CIR Dental School, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-7781-3139
Tullio GenovaDepartment of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Turin, Italy.ORCID 0000-0001-7824-8389
Giacomo BaimaBone and Dental Bioengineering Laboratory, CIR Dental School, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-9395-4967
Giovanni Nicolao BertaDepartment of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043 Orbassano, Italy.ORCID 0000-0002-3263-9349
Andrea GiuraApplied Metrology and Engineering Division, Istituto Nazionale di Ricerca Metrologica (INRiM), Strada delle Cacce 91, 10135 Turin, Italy.ORCID 0009-0000-2761-641X
Luigi RibottaApplied Metrology and Engineering Division, Istituto Nazionale di Ricerca Metrologica (INRiM), Strada delle Cacce 91, 10135 Turin, Italy.ORCID 0000-0001-5334-5246
Donatella DuraccioInstitute of Sciences and Technologies for Sustainable Energy and Mobility, National Council of Research, Strada delle Cacce 73, 10135 Turin, Italy.ORCID 0000-0001-9339-9660
Maria Giulia FagaInstitute of Sciences and Technologies for Sustainable Energy and Mobility, National Council of Research, Strada delle Cacce 73, 10135 Turin, Italy.ORCID 0000-0003-1290-3314
Federico MussanoBone and Dental Bioengineering Laboratory, CIR Dental School, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-5800-0749

Funding

Ministero dell'Università e della Ricerca Project Title -Multiscale modelling/characterisation and fabrication of nanocomposite ceramics with improved toughness (CONCERTO)
6 · The paper itself

Abstract

The improvement of the mucosal sealing around the implant represents a challenge, one that prompted research into novel materials. To this purpose, a printable poly(ε-caprolactone) (PCL)-based composite loaded with alumina-toughened zirconia (ATZ) at increasing rates of 10, 20, and 40 wt.% was prepared, using a solvent casting method with chloroform. Disks were produced by 3D printing; surface roughness, free energy and optical contact angle were measured. Oral fibroblasts (PF) and epithelial cell (SG) tests were utilized to determine the biocompatibility of the materials through cell viability assay and adhesion and spreading evaluations. The highest level of ATZ resulted in an increase in the average roughness (S

Indexed as

3D printingalumina-toughened zirconiacell viabilityearly cell responseoral fibroblastsoral keratinocytespoly(ε-caprolactone)solvent casting

Identifiers

PMID39274152
PMCPMC11398029

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.