Evidence map›Paper›PMID 39273598›Full record

ArticleInternational journal of molecular sciences2024

C-C Chemokine Receptor 7 Promotes T-Cell Acute Lymphoblastic Leukemia Invasion of the Central Nervous System via β2-Integrins.

Cesar I Cardona, Alondra Rodriguez, Vivian C Torres, Anahi Sanchez, Angel Torres, Aaron E Vazquez, Amy E Wagler, Michael A Brissette, Colin A Bill, Charlotte M Vines

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cesar I CardonaDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.
Alondra RodriguezDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.
Vivian C TorresDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.
Anahi SanchezDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.
Angel TorresDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.
Aaron E VazquezDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.
Amy E WaglerPublic Health Sciences, The University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0001-9799-6059
Michael A BrissetteDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.
Colin A BillDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.ORCID 0000-0003-0645-0363
Charlotte M VinesDepartment of Biological Sciences, The University of Texas at El Paso, El Paso, TX 79936, USA.ORCID 0000-0002-7902-8713

Funding

UTEP Border Biomedical Research CenterU54MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI Robert A. Kirken · 2019 to 2026
$35.1M
Development of a Mouse Model to Study Targeted Therapy to Prevent CNS Invasion by Pediatric T-ALLR03CA270815 · NCI · UNIVERSITY OF TEXAS EL PASO · PI VINES, CHARLOTTE M · 2023 to 2024
$154k
NCI NIH HHS R03 CA270815NIH HHS RO3 CA270815NIMHD NIH HHS U54 MD007592
6 · The paper itself

Abstract

C-C Chemokine Receptor 7 (CCR7) mediates T-cell acute lymphoblastic leukemia (T-ALL) invasion of the central nervous system (CNS) mediated by chemotactic migration to C-C chemokine ligand 19 (CCL19). To determine if a CCL19 antagonist, CCL19

Indexed as

CD18 AntigensChemokine CCL19Precursor T-Cell Lymphoblastic Leukemia-LymphomaReceptors, CCR7AnimalsCell Line, TumorCell MovementCentral Nervous SystemChemokine CCL21ChemotaxisHumansMiceNeoplasm InvasivenessCCL19 protein, humanCCR7 protein, humanCD18 AntigensChemokine CCL19Chemokine CCL21Receptors, CCR7antagonistC-C Chemokine Receptor 7integrin

Identifiers

PMID39273598
PMCPMC11395280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.