Evidence map›Paper›PMID 39273580›Full record

ArticleInternational journal of molecular sciences2024

Neutrophil Extracellular Trap Formation in Advanced Heart Failure Patients-Preliminary Report.

Tomasz Urbanowicz, Anna Olasińska-Wiśniewska, Ewelina Wojtasińska, Krzysztof J Filipiak, Małgorzata Tomaszewska, Jędrzej Sikora, Marta Krama, Zofia Radek, Kajetan Grodecki, Aleksandra Krasińska-Płachta and 5 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Increased neutrophil extracellular trap formation in left ventricular assist device driveline infections: an initial report.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2025
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tomasz UrbanowiczCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0001-8080-2764
Anna Olasińska-WiśniewskaCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0002-4213-8708
Ewelina WojtasińskaDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0003-0405-9942
Krzysztof J FilipiakDepartment of Hypertensiology, Angiology and Internal Medicine, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0002-6563-0877
Małgorzata Tomaszewska1st Cardiology Department, Poznan University of Medical Sciences, 61-107 Poznan, Poland.
Jędrzej SikoraCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0001-9823-5964
Marta KramaCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-107 Poznan, Poland.
Zofia RadekCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-107 Poznan, Poland.
Kajetan Grodecki1st Cardiology Department, Warsaw University of Medical Sciences, 02-091 Warsaw, Poland.ORCID 0000-0002-0358-5679
Aleksandra Krasińska-PłachtaDepartment of Ophthalmology, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0001-8934-2506
Beata KrasińskaDepartment of Hypertensiology, Angiology and Internal Medicine, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0002-3464-1645
Zbigniew KrasińskiDepartment of Vascular, Endovascular Surgery, Angiology and Phlebology, Poznan University of Medical Science, 61-848 Poznan, Poland.ORCID 0000-0002-2798-1959
Andrzej TykarskiDepartment of Hypertensiology, Angiology and Internal Medicine, Poznan University of Medical Sciences, 61-107 Poznan, Poland.
Marek JemielityCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0003-2442-4644
Joanna Rupa-MatysekDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 61-107 Poznan, Poland.ORCID 0000-0003-1585-6410

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In end-stage heart failure, which is characterized by persistent or progressive ventricular dysfunction despite optimal medical therapy, a left ventricular assist device (LVAD) can be beneficial. Congestive heart failure provokes inflammatory and prothrombotic activation. The aim of this study was to evaluate the serum concentration of citrullinated histone 3 (CH3) representing neutrophil extracellular trap (NET) formation in patients referred for LVAD implantation. There were 10 patients with a median age of 61 (57-65) years enrolled in a prospective single-center analysis who underwent LVAD implantation. The CH3 plasma concentration was measured preoperatively and on the 1st and 7th postoperative days, followed by control measurements on the median (Q1-3) 88th (49-143) day. The preoperative CH3 concentration strongly correlated with brain natriuretic peptide (r = 0.879,

Indexed as

Extracellular TrapsHeart-Assist DevicesHeart FailureHistonesAgedBiomarkersCitrullinationFemaleHumansMaleMiddle AgedNeutrophilsProspective StudiesBiomarkersHistonescitrullinated histone 3 (CH3)heart failure (HF)Heartmate 3left ventricular assist device (LVAD)neutrophil extracellular trap (NET)

Identifiers

PMID39273580
PMCPMC11487443

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.