Evidence map›Paper›PMID 39273574›Full record

ArticleInternational journal of molecular sciences2024

A 13-Year-Old Girl Affected by Melanocytic Tumors of the Central Nervous System-The Case.

Emilia Nowosławska, Magdalena Zakrzewska, Beata Sikorska, Jakub Zakrzewski, Bartosz Polis

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Intramedullary melanocytoma: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emilia NowosławskaDepartment of Neurosurgery, Institute of Polish Mother's Health Centre in Lodz, Rzgowska 281/289, 93-338 Lodz, Poland.
Magdalena ZakrzewskaDepartment of Molecular Pathology and Neuropathology, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.
Beata SikorskaDepartment of Molecular Pathology and Neuropathology, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.
Jakub ZakrzewskiFaculty of Medicine, Medical University of Lodz, Kosciuszki 4, 90-419 Lodz, Poland.
Bartosz PolisDepartment of Neurosurgery, Institute of Polish Mother's Health Centre in Lodz, Rzgowska 281/289, 93-338 Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary intracranial melanoma is a very rare brain tumor, especially when accompanied by benign intramedullary melanocytoma. Distinguishing between a primary central nervous system (CNS) lesion and metastatic melanoma is extremely difficult, especially when the primary cutaneous lesion is not visible. Here we report a 13-year-old girl admitted to the Neurosurgery Department of the Institute of Polish Mother's Health Centre in Lodz due to upper limb paresis. An intramedullary tumor of the cervical C3-C4 and an accompanying syringomyelic cavity C1-C7 were revealed. The child underwent partial removal of the tumor due to the risk of damage to spinal cord motor centers. The removed part of the tumor was diagnosed as melanocytoma. Eight months later, a neurological examination revealed paresis of the right sixth cranial nerve, accompanied by bilateral optic disc edema. Diagnostic imaging revealed a brain tumor. The girl underwent resection of both detected the tumors and an additional satellite lesion revealed during the surgery. The removed tumors were diagnosed as malignant melanomas in pathomorphological examination. Molecular analysis revealed

Indexed as

MelanomaAdolescentBrain NeoplasmsFemaleGTP PhosphohydrolasesHumansMembrane ProteinsMutationSpinal Cord NeoplasmsGTP PhosphohydrolasesMembrane ProteinsNRAS protein, humancentral nervous system melanomamolecular analysisneurocutaneous melanocytosisneurocutaneous phakomatosispediatric melanoma

Identifiers

PMID39273574
PMCPMC11395317

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.