Evidence map›Paper›PMID 39273568›Full record

ArticleInternational journal of molecular sciences2024

Inflammatory Intracellular Signaling in Neurons Is Influenced by Glial Soluble Factors in iPSC-Based Cell Model of

Tatiana Gerasimova, Daniil Poberezhniy, Valentina Nenasheva, Ekaterina Stepanenko, Elena Arsenyeva, Lyudmila Novosadova, Igor Grivennikov, Sergey Illarioshkin, Maria Lagarkova, Vyacheslav Tarantul and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tatiana GerasimovaLaboratory of Translative Biomedicine, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-3858-4561
Daniil PoberezhniyLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0001-7281-4714
Valentina NenashevaLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0003-3985-6466
Ekaterina StepanenkoLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0003-1451-817X
Elena ArsenyevaLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.
Lyudmila NovosadovaLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.
Igor GrivennikovLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.
Sergey IllarioshkinResearch Center of Neurology, 125367 Moscow, Russia.ORCID 0000-0002-2704-6282
Maria LagarkovaLaboratory of Translative Biomedicine, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0001-9594-1134
Vyacheslav TarantulLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.
Ekaterina NovosadovaLaboratory of Molecular Neurogenetics and Innate Immunity, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.

Funding

the Ministry of Science and Higher Education of the Russian Federation 075-15-2023-324
6 · The paper itself

Abstract

Neuroinflammation is considered to be one of the driving factors in Parkinson's disease (PD). This study was conducted using neuronal and glial cell cultures differentiated from induced pluripotent stem cells (iPSC) of healthy donors (HD) and PD patients with different

Indexed as

Induced Pluripotent Stem CellsNeurogliaNeuronsParkinson DiseaseUbiquitin-Protein LigasesCell DifferentiationCells, CulturedCulture Media, ConditionedHumansInflammationSignal TransductionCulture Media, Conditionedparkin proteinUbiquitin-Protein Ligasesgliainduced pluripotent stem cellsneuroinflammationneuronsPARK2 geneParkinson’s disease

Identifiers

PMID39273568
PMCPMC11395490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.