Evidence map›Paper›PMID 39273494›Full record

ArticleInternational journal of molecular sciences2024

Exceptional Evolution of a Squamous Odontogenic Tumor in the Jaw: Molecular Approach.

Miguel Alonso-Juarranz, Oscar De La Sen, Pablo Pérez, Maria Aranzazu González-Corchón, Santiago Cabezas-Camarero, Melchor Saiz-Pardo, Jesus Viñas-Lopez, Lucia Recio-Poveda, Luisa María Botella, Farzin Falahat

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miguel Alonso-JuarranzOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.
Oscar De La SenOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.
Pablo PérezOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.
Maria Aranzazu González-CorchónOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.
Santiago Cabezas-CamareroOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.
Melchor Saiz-PardoOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.
Jesus Viñas-LopezSecugen, Center for Biological, Research Margarita Salas, CSIC, 28040 Madrid, Spain.
Lucia Recio-PovedaDepartment of Molecular Biomedicine, Center for Biological, Research Margarita Salas, CSIC, 28040 Madrid, Spain.
Luisa María BotellaDepartment of Molecular Biomedicine, Center for Biological, Research Margarita Salas, CSIC, 28040 Madrid, Spain.ORCID 0000-0002-6310-2245
Farzin FalahatOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.

Funding

Spanish grant from MICINN PID2020-115371RB-I00
6 · The paper itself

Abstract

A squamous odontogenic tumor (SOT) is an epithelial locally benign neoplasia derived from the periodontium of the jaws. It is considered a lesion of low incidence. Predominantly, it affects the mandible, although both jaw bones may be involved. Here, we discuss the malignant clinical evolution of an SOT lesion in an 80-year-old female patient. The patient exhibited an expansive triangular lesion at the inferior right quadrant. Surgery was performed and an SOT was diagnosed (2019). Two years after, the lesion grew, and the analysis of the biopsy revealed SOT malignization with pleomorphic atypical squamous cells, characteristics of a squamous cell carcinoma (2021). Massive DNA sequencing of formalin-fixed-paraffin-embedded specimens of the initial and relapsed tumors indicated pathogenic mutations in

Indexed as

Odontogenic Tumor, SquamousAged, 80 and overFemaleHumansJaw NeoplasmsMutationOdontogenic Tumorsmalignizationpersonalized medicinerare cancerssquamous odontogenic tumor (SOT)

Identifiers

PMID39273494
PMCPMC11395408

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.