Evidence map›Paper›PMID 39273362›Full record

ArticleInternational journal of molecular sciences2024

Potential of Coffee Cherry Pulp Extract against Polycyclic Aromatic Hydrocarbons in Air Pollution Induced Inflammation and Oxidative Stress for Topical Applications.

Weeraya Preedalikit, Chuda Chittasupho, Pimporn Leelapornpisid, Natthachai Duangnin, Kanokwan Kiattisin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Tri-Culture Fermentation of Neem (Plants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. International journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weeraya PreedalikitDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-8584-8830
Chuda ChittasuphoDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-0696-9969
Pimporn LeelapornpisidFaculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Natthachai DuangninRegional Medical Science Center 1 Chiang Mai, Chiang Mai 50180, Thailand.
Kanokwan KiattisinDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Funding

Faculty of Pharmacy, Chiang Mai UniversityTA/RA scholarship from Graduate School, Chiang Mai University, Thailand
6 · The paper itself

Abstract

Airborne particulate matter (PM) contains polycyclic aromatic hydrocarbons (PAHs) as primary toxic components, causing oxidative damage and being associated with various inflammatory skin pathologies such as premature aging, atopic dermatitis, and psoriasis. Coffee cherry pulp (CCS) extract, rich in chlorogenic acid, caffeine, and theophylline, has demonstrated strong antioxidant properties. However, its specific anti-inflammatory effects and ability to protect macrophages against PAH-induced inflammation remain unexplored. Thus, this study aimed to evaluate the anti-inflammatory properties of CCS extract on RAW 264.7 macrophage cells exposed to atmospheric PAHs, compared to chlorogenic acid (CGA), caffeine (CAF), and theophylline (THP) standards. The CCS extract was assessed for its impact on the production of nitric oxide (NO) and expression of tumor necrosis factor-alpha (TNF-

Indexed as

Anti-Inflammatory AgentsOxidative StressPlant ExtractsPolycyclic Aromatic HydrocarbonsAdministration, TopicalAir PollutionAnimalsAntioxidantsCaffeineChlorogenic AcidCoffeaInflammationMacrophagesMiceNitric OxideNitric Oxide Synthase Type IIAnti-Inflammatory AgentsAntioxidantsCaffeineChlorogenic AcidNitric OxideNitric Oxide Synthase Type IIParticulate MatterPlant ExtractsPolycyclic Aromatic HydrocarbonsReactive Oxygen SpeciesTumor Necrosis Factor-alphaanti-inflammationcaffeinechlorogenic acidcoffee cherry pulpcyclooxygenase-2inducible nitric oxide synthaseinterleukin-6pollutionpolycyclic aromatic hydrocarbonstheophyllinetumor necrosis factor-alpha

Identifiers

PMID39273362
PMCPMC11395326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.