Evidence map›Paper›PMID 39273330›Full record

ArticleInternational journal of molecular sciences2024

Hepatocyte Growth Factor Modulates Corneal Endothelial Wound Healing In Vitro.

Merle Tratnig-Frankl, Nikolaus Luft, Guiseppe Magistro, Siegfried Priglinger, Andreas Ohlmann, Stefan Kassumeh

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Merle Tratnig-FranklDepartment of Ophthalmology, LMU University Hospital, Ludwig-Maximilians University Munich, Mathildenstrasse 8, 80336 Munich, Germany.
Nikolaus LuftDepartment of Ophthalmology, LMU University Hospital, Ludwig-Maximilians University Munich, Mathildenstrasse 8, 80336 Munich, Germany.ORCID 0000-0002-7815-6289
Guiseppe MagistroDepartment of Urology, Asklepios Westklinikum Hamburg GmbH, Suurheid 20, 22559 Hamburg, Germany.
Siegfried PriglingerDepartment of Ophthalmology, LMU University Hospital, Ludwig-Maximilians University Munich, Mathildenstrasse 8, 80336 Munich, Germany.
Andreas OhlmannDepartment of Ophthalmology, LMU University Hospital, Ludwig-Maximilians University Munich, Mathildenstrasse 8, 80336 Munich, Germany.ORCID 0000-0002-7101-9361
Stefan KassumehDepartment of Ophthalmology, LMU University Hospital, Ludwig-Maximilians University Munich, Mathildenstrasse 8, 80336 Munich, Germany.ORCID 0000-0003-0707-9551

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we assessed the impact of hepatocyte growth factor (HGF) on corneal endothelial cells (CECs), finding that HGF concentrations of 100-250 ng/mL significantly increased CEC proliferation by 30%, migration by 32% and improved survival under oxidative stress by 28% compared to untreated controls (

Indexed as

Cell MovementCell ProliferationEndothelium, CornealHepatocyte Growth FactorWound HealingCells, CulturedCell SurvivalEndothelial CellsEpithelial-Mesenchymal TransitionFuchs' Endothelial DystrophyHumansOxidative StressSodium-Potassium-Exchanging ATPaseHepatocyte Growth FactorHGF protein, humanSodium-Potassium-Exchanging ATPasebarriercorneaendothelial cellsepithelial cellsfunctionalityskinwound healing

Identifiers

PMID39273330
PMCPMC11395100

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.