Evidence map›Paper›PMID 39273327›Full record

ArticleInternational journal of molecular sciences2024

Thermo-Responsive Hydrogel Containing Microfluidic Chitosan Nanoparticles Loaded with

Raffaele Conte, Anna Valentino, Ilenia De Luca, Gemilson Soares Pontes, Anna Calarco, Pierfrancesco Cerruti

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raffaele ConteResearch Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-6266-4991
Anna ValentinoResearch Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0001-8041-2221
Ilenia De LucaResearch Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0003-3776-6627
Gemilson Soares PontesLaboratory of Virology and Immunology, National Institute of Amazonian Research (INPA), Manaus 69067-375, AM, Brazil.
Anna CalarcoResearch Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-1441-7662
Pierfrancesco CerrutiInstitute for Polymers, Composites, and Biomaterials (IPCB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli, Italy.

Funding

Injectable Hydrogels for treatment of periodontal disease (HYPE). National Recovery and Resilience Plan (NRRP) CN_00000033Italian Ministry of Foreign Affairs and International Cooperation (MAECI), in the frame of the NANOARBO project BR22GR04NextGenerationEU within the framework of National Biodiversity Future Center (NBFC); P2022RZ8WM
6 · The paper itself

Abstract

Periodontitis is a chronic inflammatory disease resulting from the dysbiosis of periodontal bacteria and the host's immune response, leading to tissue degradation and sustained inflammation. Traditional treatments, such as mechanical debridement and antimicrobial agents, often fail to fully eradicate pathogenic bacteria, especially in deep periodontal pockets. Consequently, the need for novel therapeutic approaches has increased the interest in bioactive natural extracts, such as that of

Indexed as

ChitosanHydrogelsNanoparticlesOpuntiaPeriodontitisPlant ExtractsAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsBiofilmsDrug CarriersDrug LiberationHumansMicePoloxamerPorphyromonas gingivalisAnti-Bacterial AgentsAnti-Inflammatory AgentsChitosanDrug CarriersHydrogelsPlant ExtractsPoloxameranti-biofilmmacrophage modulationmicrofluidic particle synthesisOpuntiaperiodontitisthermo-responsive hydrogel

Identifiers

PMID39273327
PMCPMC11395269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.