Evidence map›Paper›PMID 39273312›Full record

ArticleInternational journal of molecular sciences2024

Highly Specific Polyphenolic Colloids as Alternatives to Antimicrobials in Livestock Production.

Andrea Laconi, Alessandro Cecconello, Simone Molinari, Graziano Rilievo, Aura Cencini, Federica Tonolo, Antonie Krystofova, Hardik Nilesh Majethia, Roberta Tolosi, Eliana Schiavon and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Andrea LaconiDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0003-0102-7021
Alessandro CecconelloDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-7075-2801
Simone MolinariDepartment of Geosciences and CIRCe Centre, University of Padua, Via G. Gradenigo 6, 35129 Padua, Italy.ORCID 0000-0003-4105-4833
Graziano RilievoDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0003-4098-5636
Aura CenciniDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0009-0004-1830-9062
Federica TonoloDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-7780-8994
Antonie KrystofovaDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0009-0009-3868-8406
Hardik Nilesh MajethiaDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0003-3695-292X
Roberta TolosiDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.
Eliana SchiavonIstituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università 10, 35020 Legnaro, Italy.
Carlo NicolettoDepartment of Agronomy, Food, Natural Resources, Animals and Environment, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-0154-0485
Alessandra PiccirilloDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-6207-4721
Fabio VianelloDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-4874-7205
Massimiliano MagroDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-4644-004X

Funding

Italian Ministry of Education, University and research (MIUR) by REACT-EU PON "Ricerca e Innovazione 2014-2020"Italian Ministry of Education, University and research (MIUR) "Sentinel" and "Ecosistema dell'Innovazione"Italian Ministry of Education, University and research (MIUR) funds "iNEST- Interconnected Nord-Est Innovation ECS00000043".University of Padua "Supporting TAlent in ReSearch @ University of Padua - STARS Grants" 2023
6 · The paper itself

Abstract

The dispersion of antibiotics in livestock farming represents a health concern worldwide, contributing to the spread of antimicrobial-resistant bacteria through animals, the environment, and humans. Phenolic compounds could be alternatives to antibiotics, once drawbacks such as their low water solubility, bioavailability, and reduced stability are overcome. Although nano- or micro-sized formulations could counter these shortcomings, they do not represent cost-effective options. In this study, three phenolic compounds, obtained from wood-processing manufacturers, were characterized, revealing suitable features such as their antioxidant activity, size, and chemical and colloidal stability for in-field applications. The minimum inhibitory concentration (MIC) of these colloidal suspensions was measured against six bacterial strains isolated from livestock. These particles showed different inhibition behaviors: Colloidal chestnut was effective against one of the most threatening antibiotic-resistant pathogens, i.e.,

Indexed as

ColloidsLivestockMicrobial Sensitivity TestsPolyphenolsAnimalsAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsEscherichia coliStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsColloidsPolyphenolsAMRantimicrobialsnanoparticleswood industry by-products

Identifiers

PMID39273312
PMCPMC11395071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.