Evidence map›Paper›PMID 39273208›Full record

ArticleInternational journal of molecular sciences2024

Oral Administration of Probiotic

Toshiaki Ishii, Motohiro Kaya, Yoshikage Muroi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Toshiaki IshiiDepartment of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Hokkaido, Japan.ORCID 0000-0002-6431-3263
Motohiro KayaCenter for Industry-University Collaboration, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Hokkaido, Japan.
Yoshikage MuroiDepartment of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Hokkaido, Japan.

Funding

The Japan Society for the Promotion of Science A Grant-in-Aid for Scientific Research (C) [23K05531] (to T.I.)
6 · The paper itself

Abstract

Epilepsy is a chronic neurological disorder characterized by recurrent seizures that affects over 70 million people worldwide. Although many antiepileptic drugs that block seizures are available, they have little effect on preventing and curing epilepsy, and their side effects sometimes lead to serious morbidity. Therefore, prophylactic agents with anticonvulsant properties and no adverse effects need to be identified. Recent studies on probiotic administration have reported a variety of beneficial effects on the central nervous system via the microbiota-gut-brain axis. In this study, we investigated the effects of the oral administration of

Indexed as

Bifidobacterium breveDisease Models, AnimalKindling, NeurologicPentylenetetrazoleProbioticsProtein Serine-Threonine KinasesSeizuresSignal TransductionAdministration, OralAnimalsHippocampusMaleMicePhosphorylationProto-Oncogene Proteins c-aktScaffold Protein ILKPentylenetetrazoleProtein Serine-Threonine KinasesProto-Oncogene Proteins c-aktScaffold Protein ILKAktBifidobacterium breve A1 (B. breve A1)Cpd22epilepsyhippocampusintegrinintegrin-linked kinase (ILK)MMP-9neuropsinpentylenetetrazole (PTZ)seizure

Identifiers

PMID39273208
PMCPMC11395544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.