Evidence map›Paper›PMID 39273087›Full record

ReviewInternational journal of molecular sciences2024

The AP-2 Family of Transcription Factors-Still Undervalued Regulators in Gastroenterological Disorders.

Yi-Jin Yu, Damian Kołat, Żaneta Kałuzińska-Kołat, Zhu Liang, Bo-Qiang Peng, Yun-Feng Zhu, Kai Liu, Jia-Xin Mei, Gang Yu, Wei-Han Zhang and 4 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yi-Jin YuDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0002-9983-7910
Damian KołatDepartment of Functional Genomics, Medical University of Lodz, 90-752 Lodz, Lodzkie, Poland.ORCID 0000-0002-1086-3796
Żaneta Kałuzińska-KołatDepartment of Functional Genomics, Medical University of Lodz, 90-752 Lodz, Lodzkie, Poland.ORCID 0000-0002-2335-3293
Zhu LiangNuffield Department of Medicine, Target Discovery Institute, University of Oxford, Center for Medicines Discovery, Oxford OX1 2JD, UK.
Bo-Qiang PengDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Yun-Feng ZhuDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Kai LiuDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Jia-Xin MeiDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Gang YuDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Wei-Han ZhangDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Xiao-Long ChenDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Kun YangDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Jian-Kun HuDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Lin-Yong ZhaoDepartment of General Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy-Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.

Funding

National Natural Science Foundation of China 82102998
6 · The paper itself

Abstract

Activating enhancer-binding protein 2 (AP-2) is a family of transcription factors (TFs) that play crucial roles in regulating embryonic and oncogenic development. In addition to splice isoforms, five major family members encoded by the

Indexed as

Transcription Factor AP-2AnimalsGastrointestinal DiseasesHumansTranscription Factor AP-2AP-2colorectal cancergastric cancergastroenterological disordersTFAP2transcription factors

Identifiers

PMID39273087
PMCPMC11394946

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.