Evidence map›Paper›PMID 39273035›Full record

ArticleCells2024

1,25-Dihydroxyvitamin D Enhances the Regenerative Function of Lgr5

Nisar Ali Shaikh, Chenfan Liu, Yue Yin, David J Baylink, Xiaolei Tang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nisar Ali ShaikhDepartment of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY 11548, USA.ORCID 0000-0001-5147-7608
Chenfan LiuDepartment of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY 11548, USA.
Yue YinDepartment of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY 11548, USA.ORCID 0000-0003-1960-7171
David J BaylinkDivision of Regenerative Medicine, Department of Medicine, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA.
Xiaolei TangDepartment of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY 11548, USA.

Funding

Targeting Intestinal Stem Cells to Augment the Repair of Epithelial BarrierR21AI142170 · NIAID · LONG ISLAND UNIVERSITY C. W. POST CENTER · PI TANG, XIAOLEI · 2019 to 2020
$456k
American Association of Immunologists 2022NIAID NIH HHS R21 AI142170NIH HHS 1R21AI142170-19A1
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder in the intestines without a cure. Current therapies suppress inflammation to prevent further intestinal damage. However, healing already damaged intestinal epithelia is still an unmet medical need. Under physiological conditions, Lgr5

Indexed as

Receptors, G-Protein-CoupledStem CellsVitamin DAnimalsCell DifferentiationCell ProliferationColitisIntestinal MucosaIntestinesMiceMice, Inbred C57BLRegeneration1,25-dihydroxyvitamin DLgr5 protein, mouseReceptors, G-Protein-CoupledVitamin D1,25-dihydroxyvitamin Dinflammatory bowel diseaseLgr5+ intestinal stem cellsvitamin D receptor

Identifiers

PMID39273035
PMCPMC11394149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.