Evidence map›Paper›PMID 39272939›Full record

ArticleCancers2024

Haemodynamic Forces: Emerging Markers of Ventricular Remodelling in Multiple Myeloma Cardiovascular Baseline Risk Assessment.

Anna Colomba, Anna Astarita, Giulia Mingrone, Lorenzo Airale, Cinzia Catarinella, Fabrizio Vallelonga, Dario Leone, Marco Cesareo, Arianna Paladino, Sara Bringhen and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Anna ColombaCandiolo Cancer Institute, FPO—IRCCS, 10060 Candiolo, TO, Italy.ORCID 0009-0002-2675-8015
Anna AstaritaDepartment of Medical Sciences, University of Turin, 10126 Turin, Italy.
Giulia MingroneCandiolo Cancer Institute, FPO—IRCCS, 10060 Candiolo, TO, Italy.ORCID 0000-0002-7360-728X
Lorenzo AiraleDepartment of Medical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-5407-5188
Cinzia CatarinellaDepartment of Medical Sciences, University of Turin, 10126 Turin, Italy.
Fabrizio VallelongaCandiolo Cancer Institute, FPO—IRCCS, 10060 Candiolo, TO, Italy.ORCID 0000-0002-4628-6767
Dario LeoneCandiolo Cancer Institute, FPO—IRCCS, 10060 Candiolo, TO, Italy.ORCID 0000-0002-2904-3130
Marco CesareoDepartment of Medical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-5459-9942
Arianna PaladinoCandiolo Cancer Institute, FPO—IRCCS, 10060 Candiolo, TO, Italy.
Sara BringhenSSD Clinical Trial in Oncoematologia e Mieloma Multiplo, Division of Hematology, AOU Città della Salute e della Scienza University Hospital, 10126 Turin, Italy.ORCID 0000-0003-4539-6363
Francesca GaySSD Clinical Trial in Oncoematologia e Mieloma Multiplo, Division of Hematology, AOU Città della Salute e della Scienza University Hospital, 10126 Turin, Italy.ORCID 0000-0002-8619-412X
Gianni PedrizzettiDepartment of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-2886-7653
Franco VeglioDepartment of Medical Sciences, University of Turin, 10126 Turin, Italy.
Alberto MilanCandiolo Cancer Institute, FPO—IRCCS, 10060 Candiolo, TO, Italy.ORCID 0000-0002-8863-8572

Funding

Italian Ministry of Education and Research PRIN 2022AJT27Y
6 · The paper itself

Abstract

Multiple myeloma (MM) affects a population with a high prevalence of cardiovascular (CV) disease. These patients benefit from an accurate CV risk evaluation in order to choose the safest drug regimen. Haemodynamic forces (HDFs) analysis allows for the earlier detection of myocardial damage compared with standard markers; the role played by MM in HDFs alteration, with or without the influence of hypertension, is yet to be studied. Therefore, we aimed to identify differences in HDFs analysis in patients with MM, hypertension or both versus normotensive non-oncologic subjects. A total of 173 patients (MM hypertensive patients, MMHT; MM normotensive patients, MMNT; non-oncologic hypertensive patients, CoHT; and non-oncologic normotensive patients, CoNT) underwent transthoracic echocardiography for HDFs analysis and pulse wave velocity (PWV) assessment. Hypertensive patients (MMHT, CoHT) showed decreased ejection fraction (EF), global longitudinal strain (GLS) and HDFs values compared with CoNT, whereas ventricular mass (LVMi) and PWV increased. MMNT displayed a significant reduction in systolic HDFs (

Indexed as

arterial hypertensioncardiovascular riskechocardiographyhaemodynamic forcesmultiple myeloma

Identifiers

PMID39272939
PMCPMC11393942

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.