Evidence map›Paper›PMID 39272935›Full record

ArticleCancers2024

The Impact of Melanoma Imaging Biomarker Cues on Detection Sensitivity and Specificity in Melanoma versus Clinically Atypical Nevi.

Rosario Agüero, Kendall L Buchanan, Cristián Navarrete-Dechent, Ashfaq A Marghoob, Jennifer A Stein, Michael S Landy, Sancy A Leachman, Kenneth G Linden, Sandra Garcet, James G Krueger and 1 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rosario AgüeroDepartment of Dermatology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile.ORCID 0000-0001-5476-8494
Kendall L BuchananDepartment of Dermatology, Medical College of Georgia at Augusta University, Augusta, GA 30904, USA.ORCID 0000-0002-8003-3421
Cristián Navarrete-DechentMelanoma and Skin Cancer Unit, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile.ORCID 0000-0003-4040-3640
Ashfaq A MarghoobMemorial Sloan Kettering Skin Cancer Center, New York, NY 10022, USA.ORCID 0000-0001-6068-0114
Jennifer A SteinRonald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-0962-4982
Michael S LandyDepartment of Psychology, New York University, New York, NY 10003, USA.ORCID 0000-0002-2079-4552
Sancy A LeachmanDermatology Department, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0001-9140-0648
Kenneth G LindenDermatology Department, University of California Irvine, Irvine, CA 92868, USA.ORCID 0009-0006-4681-2452
Sandra GarcetLaboratory for Investigative Dermatology, Rockefeller University, New York, NY 10065, USA.
James G KruegerLaboratory for Investigative Dermatology, Rockefeller University, New York, NY 10065, USA.ORCID 0000-0002-3775-1778
Daniel S GareauLaboratory for Investigative Dermatology, Rockefeller University, New York, NY 10065, USA.ORCID 0000-0002-9759-1198

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
SHAPE REPRESENTATION AND MULTIPLE DEPTH CUESR01EY008266 · NEI · NEW YORK UNIVERSITY · PI MICHAEL S LANDY · 1989 to 2026
$7.7M
Sensory Cue Integration in Melanoma ScreeningR21CA240254 · NCI · ROCKEFELLER UNIVERSITY · PI GAREAU, DANIEL SUMMER · 2020 to 2020
$413k
NCI NIH HHS P30 CA008748NCI NIH HHS R21 CA240254NEI NIH HHS R01 EY008266NIH HHS 1R21CA240254-20A1
6 · The paper itself

Abstract

Incorporation of dermoscopy and artificial intelligence (AI) is improving healthcare professionals' ability to diagnose melanoma earlier, but these algorithms often suffer from a "black box" issue, where decision-making processes are not transparent, limiting their utility for training healthcare providers. To address this, an automated approach for generating melanoma imaging biomarker cues (IBCs), which mimics the screening cues used by expert dermoscopists, was developed. This study created a one-minute learning environment where dermatologists adopted a sensory cue integration algorithm to combine a single IBC with a risk score built on many IBCs, then immediately tested their performance in differentiating melanoma from benign nevi. Ten participants evaluated 78 dermoscopic images, comprised of 39 melanomas and 39 nevi, first without IBCs and then with IBCs. Participants classified each image as melanoma or nevus in both experimental conditions, enabling direct comparative analysis through paired data. With IBCs, average sensitivity improved significantly from 73.69% to 81.57% (

Indexed as

artificial intelligencedermoscopyimaging biomarkersmelanoma

Identifiers

PMID39272935
PMCPMC11394255

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.