Evidence map›Paper›PMID 39272880›Full record

ArticleCancers2024

Accuracy of GynTect

Heike Hoyer, Cornelia Scheungraber, Grit Mehlhorn, Ingke Hagemann, Sarah Scherbring, Linn Wölber, Annett Petzold, Kristina Wunsch, Martina Schmitz, Monika Hampl and 4 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Heike HoyerInstitut für Medizinische Statistik, Informatik, Datenwissenschaften (IMSID), Universitätsklinikum Jena, 07743 Jena, Germany.
Cornelia ScheungraberFrauenarztpraxis, Westbahnhofstraße 2, 07745 Jena, Germany.
Grit MehlhornFrauenarztpraxis, Neustädter Kirchenplatz 1A, 91054 Erlangen, Germany.
Ingke Hagemannabts+partner Partnerschaftsgesellschaft, Prüner Gang 7, 24103 Kiel, Germany.
Sarah ScherbringFachärzte für Frauenheilkunde und Geburtshilfe, Karrenführerstraße 1-3, 38100 Braunschweig, Germany.
Linn WölberKlinik für Gynäkologie, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-9578-3049
Annett PetzoldKlinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin, Universitätsklinikum Jena, 07747 Jena, Germany.
Kristina WunschOncgnostics GmbH, Löbstedter Str. 41, 07749 Jena, Germany.
Martina SchmitzOncgnostics GmbH, Löbstedter Str. 41, 07749 Jena, Germany.ORCID 0000-0003-2430-3500
Monika HamplUniversitätsfrauenklinik Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Gerd BöhmerInstitut für Zytologie und Dysplasie (IZD), Theaterstr. 14, 30159 Hannover, Germany.
Peter HillemannsKlinik für Frauenheilkunde und Geburtshilfe, Medizinische Hochschule Hannover (MHH), 30625 Hannover, Germany.
Ingo B RunnebaumKlinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin, Universitätsklinikum Jena, 07747 Jena, Germany.
Matthias DürstKlinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin, Universitätsklinikum Jena, 07747 Jena, Germany.ORCID 0000-0003-1235-1150

Funding

Open Access Publication Fund of the Thüringer Universitäts- und Landesbibliothek Jena German Research Foundation Project-Nr. 512648189
6 · The paper itself

Abstract

Post-treatment follow-up in women with CIN3 is mandatory due to relapse in up to 15% of patients within 2 years. Standard follow-up care based on hrHPV-DNA/cytology co-testing has high sensitivity but limited specificity. The aim of our proof-of-concept case-control study was to evaluate the performance of the methylation test GynTect

Indexed as

cervical intraepithelial neoplasia (CIN)DNA methylationhrHPVpost-treatment surveillancerecurrent CIN

Identifiers

PMID39272880
PMCPMC11394525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.