Evidence map›Paper›PMID 39272848›Full record

ArticleCancers2024

Expression Analysis of Circulating microRNAs in Saliva and Plasma for the Identification of Clinically Relevant Biomarkers for Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders.

Federica Rocchetti, Gianluca Tenore, Federica Macali, Teresa Vicidomini, Gian Marco Podda, Paolo Junior Fantozzi, Valentina Silvestri, Virginia Porzio, Virginia Valentini, Laura Ottini and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Federica RocchettiDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Gianluca TenoreDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-9963-8052
Federica MacaliDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Teresa VicidominiDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Gian Marco PoddaDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-4981-5396
Paolo Junior FantozziDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-6807-3391
Valentina SilvestriDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0712-9379
Virginia PorzioDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Virginia ValentiniDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-3393-7185
Laura OttiniDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-8030-0449
Antonio Giovanni RichettaDepartment of Internal Medicine and Medical Specialties, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-8755-9178
Valentino ValentiniDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Marco Della MonacaDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-6235-9754
Camilla GrengaDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-7822-5953
Antonella PolimeniDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-2679-7607
Umberto RomeoDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-2439-2187

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to evaluate the expression of salivary and plasmatic miRNAs as diagnostic biomarkers in patients with oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs). A total of 25 patients were divided into three groups, according to their diagnosis: OSCC patients (

Indexed as

liquid biopsymicroRNAsnon-invasive biomarkersoral potentially malignant disordersoral squamous cell carcinoma

Identifiers

PMID39272848
PMCPMC11394426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.