Evidence map›Paper›PMID 39272743›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Identification of a New and Effective Marker Combination for a Standardized and Automated Bin-Based Basophil Activation Test (BAT) Analysis.

Johannes Groffmann, Ines Hoppe, Wail Abbas Nasser Ahmed, Yen Hoang, Stefanie Gryzik, Andreas Radbruch, Margitta Worm, Kirsten Beyer, Ria Baumgrass

Erratum issuedAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Johannes GroffmannGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, 10117 Berlin, Germany.
Ines HoppeGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, 10117 Berlin, Germany.
Wail Abbas Nasser AhmedGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, 10117 Berlin, Germany.ORCID 0000-0002-8102-9248
Yen HoangGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, 10117 Berlin, Germany.ORCID 0000-0001-8956-1709
Stefanie GryzikGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, 10117 Berlin, Germany.
Andreas RadbruchGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, 10117 Berlin, Germany.
Margitta WormDivision of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-3449-1245
Kirsten BeyerDepartment of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Ria BaumgrassGerman Rheumatology Research Center (DRFZ), A Leibniz Institute, 10117 Berlin, Germany.

Funding

German Federal Ministry of Education and Research (BMBF) Wheat-A-BAIC (01EA2001D) and MelAutim (01ZX1905C)
6 · The paper itself

Abstract

(1) Background: The basophil activation test (BAT) is a functional whole blood-based ex vivo assay to quantify basophil activation after allergen exposure by flow cytometry. One of the most important prerequisites for the use of the BAT in the routine clinical diagnosis of allergies is a reliable, standardized and reproducible data analysis workflow. (2) Methods: We re-analyzed a public mass cytometry dataset from peanut (PN) allergic patients (

Indexed as

basophil activation testcombinatorial protein expressionhigh-dimensional cytometry datamass cytometry datamulti-parametric analysisre-analysis

Identifiers

PMID39272743
PMCPMC11394212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.