Evidence map›Paper›PMID 39272668›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Dynamics of Cognitive Impairment in MCI Patients over a Three-Year Period: The Informative Role of Blood Biomarkers, Neuroimaging, and Genetic Factors.

Irina Morozova, Yana Zorkina, Alexander Berdalin, Anna Ikonnikova, Marina Emelyanova, Elena Fedoseeva, Olga Antonova, Dmitry Gryadunov, Alisa Andryushchenko, Valeriya Ushakova and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Irina MorozovaMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.ORCID 0000-0002-2102-4111
Yana ZorkinaMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.ORCID 0000-0003-0247-2717
Alexander BerdalinMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.ORCID 0000-0001-5387-4367
Anna IkonnikovaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-8434-5916
Marina EmelyanovaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-3681-4308
Elena FedoseevaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-1134-1401
Olga AntonovaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Dmitry GryadunovCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-3183-318X
Alisa AndryushchenkoMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.
Valeriya UshakovaMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.
Olga AbramovaMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.ORCID 0000-0001-8793-1833
Angelina ZeltserMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.
Marat KurmishevMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.
Victor SavilovMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.
Natalia OsipovaMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.ORCID 0000-0002-3023-2393
Irina PreobrazhenskayaDepartment of Nervous Diseases and Neurosurgery, I. M. Sechenov First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia.ORCID 0000-0002-9097-898X
Georgy KostyukMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.
Anna MorozovaMental-Health Clinic No. 1 Named after N.A. Alekseev, 115191 Moscow, Russia.

Funding

the Moscow Centre for Innovative Technologies in Healthcare 0803-4/23 (Agreement No. 0803-4/23-1NIR)
6 · The paper itself

Abstract

Given the high growth rates of cognitive decline among the elderly population and the lack of effective etiological treatments, early diagnosis of cognitive impairment progression is an imperative task for modern science and medicine. It is of particular interest to identify predictors of an unfavorable subsequent course of cognitive disorders, specifically, rapid progression. Our study assessed the informative role of various risk factors on the dynamics of cognitive impairment among mild cognitive impairment (MCI) patients. The study included patients with MCI (

Indexed as

APOEcognitive declinegenetic risklong-term studyMCIMMSEMOCApolygenic risk

Identifiers

PMID39272668
PMCPMC11394601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.