Evidence map›Paper›PMID 39272662›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Diagnostic Performance of a Deep Learning-Powered Application for Aortic Dissection Triage Prioritization and Classification.

Vladimir Laletin, Angela Ayobi, Peter D Chang, Daniel S Chow, Jennifer E Soun, Jacqueline C Junn, Marlene Scudeler, Sarah Quenet, Maxime Tassy, Christophe Avare and 2 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vladimir LaletinAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.ORCID 0000-0003-3960-4218
Angela AyobiAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.ORCID 0000-0002-4351-6782
Peter D ChangDepartment of Radiological Sciences, University of California Irvine, Irvine, CA 92697, USA.ORCID 0000-0001-7645-7865
Daniel S ChowDepartment of Radiological Sciences, University of California Irvine, Irvine, CA 92697, USA.
Jennifer E SounDepartment of Radiological Sciences, University of California Irvine, Irvine, CA 92697, USA.
Jacqueline C JunnDepartment of Radiology and Imaging Science, Emory University Hospital, Atlanta, GA 30322, USA.
Marlene ScudelerAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.
Sarah QuenetAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.
Maxime TassyAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.ORCID 0009-0008-7755-7356
Christophe AvareAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.ORCID 0009-0009-2943-3460
Mar Roca-SogorbAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.
Yasmina ChaibiAvicenna.AI, 375 Avenue du Mistral, 13600 La Ciotat, France.ORCID 0000-0002-9734-172X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This multicenter retrospective study evaluated the diagnostic performance of a deep learning (DL)-based application for detecting, classifying, and highlighting suspected aortic dissections (ADs) on chest and thoraco-abdominal CT angiography (CTA) scans. CTA scans from over 200 U.S. and European cities acquired on 52 scanner models from six manufacturers were retrospectively collected and processed by CINA-CHEST (AD) (Avicenna.AI, La Ciotat, France) device. The diagnostic performance of the device was compared with the ground truth established by the majority agreement of three U.S. board-certified radiologists. Furthermore, the DL algorithm's time to notification was evaluated to demonstrate clinical effectiveness. The study included 1303 CTAs (mean age 58.8 ± 16.4 years old, 46.7% male, 10.5% positive). The device demonstrated a sensitivity of 94.2% [95% CI: 88.8-97.5%] and a specificity of 97.3% [95% CI: 96.2-98.1%]. The application classified positive cases by the AD type with an accuracy of 99.5% [95% CI: 98.9-99.8%] for type A and 97.5 [95% CI: 96.4-98.3%] for type B. The application did not miss any type A cases. The device flagged 32 cases incorrectly, primarily due to acquisition artefacts and aortic pathologies mimicking AD. The mean time to process and notify of potential AD cases was 27.9 ± 8.7 s. This deep learning-based application demonstrated a strong performance in detecting and classifying aortic dissection cases, potentially enabling faster triage of these urgent cases in clinical settings.

Indexed as

AI-based solution for radiologyaortic dissectiondeep learningemergency radiologymachine learning diagnostic performancemedical and biomedical image processingmedical imaging automated analysis

Identifiers

PMID39272662
PMCPMC11393899

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.