Evidence map›Paper›PMID 39272649›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Targeted Prostate Biopsy: How, When, and Why? A Systematic Review.

Giacomo Rebez, Maria Barbiero, Franco Alchiede Simonato, Francesco Claps, Salvatore Siracusano, Rosa Giaimo, Gabriele Tulone, Fabio Vianello, Alchiede Simonato, Nicola Pavan

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. An interpretableEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giacomo RebezUrology Unit, Dipartimento Chirurgico Area Isontina, Azienda Sanitaria Universitaria Giuliano Isontina, 34170 Gorizia, Italy.ORCID 0000-0001-7938-1579
Maria BarbieroDepartment of Medical, Surgical and Health Science, Urology Clinic, University of Trieste, 34100 Trieste, Italy.
Franco Alchiede SimonatoMedical School, University of Genoa, 16100 Genoa, Italy.ORCID 0000-0002-1764-8001
Francesco ClapsDepartment of Medical, Surgical and Health Science, Urology Clinic, University of Trieste, 34100 Trieste, Italy.ORCID 0000-0003-2812-5553
Salvatore SiracusanoDepartment of Urology, University of L'Aquila, 67100 L'Aquila, Italy.
Rosa GiaimoUrology Clinic, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, 90127 Palermo, Italy.
Gabriele TuloneUrology Clinic, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, 90127 Palermo, Italy.
Fabio VianelloUrology Unit, Dipartimento Chirurgico Area Isontina, Azienda Sanitaria Universitaria Giuliano Isontina, 34170 Gorizia, Italy.
Alchiede SimonatoUrology Clinic, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-9513-4869
Nicola PavanUrology Clinic, Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-7355-7625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveProstate cancer, the second most diagnosed cancer among men, requires precise diagnostic techniques to ensure effective treatment. This review explores the technological advancements, optimal application conditions, and benefits of targeted prostate biopsies facilitated by multiparametric magnetic resonance imaging (mpMRI).

methodsA systematic literature review was conducted to compare traditional 12-core systematic biopsies guided by transrectal ultrasound with targeted biopsy techniques using mpMRI. We searched electronic databases including PubMed, Scopus, and Web of Science from January 2015 to December 2024 using keywords such as "targeted prostate biopsy", "fusion prostate biopsy", "cognitive prostate biopsy", "MRI-guided biopsy", and "transrectal ultrasound prostate biopsy". Studies comparing various biopsy methods were included, and data extraction focused on study characteristics, patient demographics, biopsy techniques, diagnostic outcomes, and complications.

conclusionmpMRI-guided targeted biopsies enhance the detection of clinically significant prostate cancer while reducing unnecessary biopsies and the detection of insignificant cancers. These targeted approaches preserve or improve diagnostic accuracy and patient outcomes, minimizing the risks associated with overdiagnosis and overtreatment. By utilizing mpMRI, targeted biopsies allow for precise targeting of suspicious regions within the prostate, providing a cost-effective method that reduces the number of biopsies performed. This review highlights the importance of integrating advanced imaging techniques into prostate cancer diagnosis to improve patient outcomes and quality of life.

Indexed as

diagnostic accuracymultiparametric MRIprostate cancer detectiontargeted prostate biopsytransrectal ultrasound

Identifiers

PMID39272649
PMCPMC11394632

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.