Evidence map›Paper›PMID 39272177›Full record

ArticleParasites & vectors2024

Evaluation of a long-lasting microbial larvicide against Culex quinquefasciatus and Aedes aegypti under laboratory and a semi-field trial.

Hyago Luiz Rique, Heverly Suzany Gouveia Menezes, Maria Alice Varjal Melo-Santos, Maria Helena Neves Lobo Silva-Filha

Abstract read
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyago Luiz RiqueDepartament of Entomology, Instituto Aggeu Magalhães-Fiocruz, Av. Moraes Rego S/N, Recife, PE, 50740-465, Brazil.
Heverly Suzany Gouveia MenezesDepartament of Entomology, Instituto Aggeu Magalhães-Fiocruz, Av. Moraes Rego S/N, Recife, PE, 50740-465, Brazil.
Maria Alice Varjal Melo-SantosDepartament of Entomology, Instituto Aggeu Magalhães-Fiocruz, Av. Moraes Rego S/N, Recife, PE, 50740-465, Brazil.
Maria Helena Neves Lobo Silva-FilhaDepartament of Entomology, Instituto Aggeu Magalhães-Fiocruz, Av. Moraes Rego S/N, Recife, PE, 50740-465, Brazil. mhelena.neves@fiocruz.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico grant 400747/2019-7Fundação de Apoio à Ciência e Tecnologia do Estado de Pernambuco IBPG-0204-2.13/21Fundação Oswaldo Cruz grant VPPCB-007-FIO-18-2-64
6 · The paper itself

Abstract

backgroundMicrobial larvicides containing both LysiniBacillus sphaericus and Bacillus thuringiensis svar. israelensis (Bti) insecticidal crystals can display advantages for mosquito control. This includes a broader action against larvae that are refractory to the Binary (Bin) toxin from L. sphaericus, as Bin-resistant Culex quinquefasciatus and Aedes aegypti naturally refractory larvae, which often co-habit urban areas of endemic countries for arboviruses. Our principal goal was to assess the toxicity of a combined L. sphaericus/Bti larvicide (Vectomax FG™) to Cx. quinquefasciatus (susceptible CqS and Bin-resistant CqR) and Ae. aegypti (Rocke) and to determine its persistence in the breeding sites with those larvae.

methodsThe toxicity of a combined L. sphaericus/Bti product (VectoMax FG™) to larvae was performed using bioassays, and persistence was evaluated in simulate field trials carried out under the shade, testing two label concentrations during 12 weeks. A laboratory strain SREC, established with CqS and CqR larvae, was kept during four generations to evaluate the ability of the L. sphaericus/Bti to eliminate resistant larvae.

resultsThe L. sphaericus/Bti showed toxicity (mg/L) to larvae from all strains with a decreasing pattern for CqS (LC

conclusionsOur results showed the high efficacy and persistence of the L. sphaericus/Bti larvicide to control Cx. quinquefasciatus and Ae. aegypti that might cohabit breeding sites. These findings demonstrated that such larvicides can be an effective tool for controlling those species in urban areas with a low potential for selecting resistance.

Indexed as

AedesBacillaceaeBacillus thuringiensisCulexInsecticidesLarvaMosquito ControlPest Control, BiologicalAnimalsInsecticide ResistanceMosquito VectorsInsecticidesBacterial toxinsBtiLysinibacillus sphaericusMosquito controlResistanceVectomax

Identifiers

PMID39272177
PMCPMC11401406

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.