ArticleMolecular horticulture2024
Loss-of-function mutation in anthocyanidin reductase activates the anthocyanin synthesis pathway in strawberry.
Article in Molecular horticulture, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- ZmHPATR1 orchestrates phyllosphere organic acid flux to recruit Sphingomonas and enhance resistance of maize to Curvularia leaf spot.The New phytologist · 2026Article
- Multifaceted mechanisms underlying species- and cultivar-associated differential anthocyanin accumulation in fruits.Horticulture research · 2026Article
- Spatial control of anthocyanin and proanthocyanidin production in tomato fruits by competitive MBW complexes to promote seed dispersal.Plant communications · 2026Article
- Multi-Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum.Plant biotechnology journal · 2026Article
- Identification of a unique tea germplasm exhibiting hyperaccumulation of trans-catechins and its molecular regulatory mechanism.Food chemistry. Molecular sciences · 2026Article
- A single nucleotide mutation in FngMYB10 causes white fruit phenotype in Fragaria nilgerrensis.BMC plant biology · 2026Article
- Article
- Overexpression of Anthocyanidin Reductase Increases Flavonoids Content to Combat Fusarium Wilt in the Root Xylem of Vernicia montana.Molecular plant pathology · 2026Article
- FaTRAB1, a bZIP transcription factor, enhances anthocyanin biosynthesis in strawberry leaves via tissue-specific regulation.PLoS genetics · 2025Article
- Recent advances in biosynthesis and regulation of strawberry anthocyanins.Horticulture research · 2025Article
- The Light-RegulatedInternational journal of molecular sciences · 2025Article
- Transcriptome and Metabolome Profiling Provide Insights into Flavonoid Biosynthesis and the Mechanism of Color Formation inPlants (Basel, Switzerland) · 2025Article
- Novel Targets for Fruit Conservation Strategies Revealed by Omics Studies: A Systematic Review and Meta-Analysis.International journal of food science · 2025Review
- Seasonal dynamics and molecular regulation of flavonoid biosynthesis inFrontiers in plant science · 2025Article
- Article
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10 authors.
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Abstract
Fruit color substantially affects consumer preferences, with darker red strawberries being economically more valuable due to their higher anthocyanin content. However, the molecular basis for the dark red coloration remains unclear. Through screening of an ethyl methanesulfonate mutant library, we identified a rg418 mutant, that demonstrated anthocyanin accumulation during early fruit development stages. Furthermore, the ripening fruits of this mutant had higher anthocyanin content than wild-type (WT) fruits. An analysis of flavonoid content in WT and rg418 mutant fruits revealed substantial changes in metabolic fluxes, with the mutant exhibiting increased levels of anthocyanins and flavonols and decreased levels of proanthocyanidins. Bulked sergeant analysis sequencing indicated that the mutant gene was anthocyanidin reductase (ANR), a key gene in the proanthocyanidin synthesis pathway. Furthermore, transcriptome sequencing revealed the increased expression of MYB105 during the early development stage of mutant fruits, which promoted the expression of UFGT (UDP-glucose flavonoid 3-O-glucosyltransferase), a key gene involved in anthocyanin synthesis, thus substantially enhancing the anthocyanin content in the mutant fruits. Additionally, mutating ANR in a white-fruited strawberry variant (myb10 mutant) resulted in appealing pink-colored fruits, suggesting the diverse roles of ANR in fruit color regulation. Our study provides valuable theoretical insights for improving strawberry fruit color.
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