Evidence map›Paper›PMID 39272046›Full record

SynthesisBMC musculoskeletal disorders2024

Previous lumbar spine fusion increases the risk of dislocation following total hip arthroplasty in patients with hip-spine syndrome: a systematic review and meta-analysis.

Ashton Huppert, Luca Ambrosio, Kenneth Nwosu, Annie Pico, Fabrizio Russo, Gianluca Vadalà, Rocco Papalia, Vincenzo Denaro

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. The invisible hip: radiographic "misses" in hip-spine syndrome and the diagnostic disparity between orthopedic surgeons and neurosurgeons.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  3. Complication Rates of Hip-Spine Syndrome Patients With Total Hip Arthroplasty and Lumbar Spine Surgery.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashton Huppert *University of Arizona College of Medicine, Phoenix, USA.
Luca Ambrosio *Research Unit of Orthopaedic and Trauma Surgery, Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University Hospital Foundation, Via Alvaro del Portillo 200, Rome, 00128, Italy.
Kenneth NwosuSouth Sound Neurosurgery, Puyallup, USA.
Annie PicoUniversity of Arizona College of Medicine, Phoenix, USA.
Fabrizio RussoResearch Unit of Orthopaedic and Trauma Surgery, Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University Hospital Foundation, Via Alvaro del Portillo 200, Rome, 00128, Italy.
Gianluca VadalàResearch Unit of Orthopaedic and Trauma Surgery, Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University Hospital Foundation, Via Alvaro del Portillo 200, Rome, 00128, Italy. g.vadala@policlinicocampus.it.
Rocco PapaliaResearch Unit of Orthopaedic and Trauma Surgery, Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University Hospital Foundation, Via Alvaro del Portillo 200, Rome, 00128, Italy.
Vincenzo DenaroOperative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Funding

Italian Workers' Compensation Authority (INAIL) BRIC-2021 ID4
6 · The paper itself

Abstract

backgroundWith life expectancy on the rise, there has been an increase in patients with concomitant degenerative hip and spine pathology, defined as hip-spine syndrome (HSS). Patients affected by HSS may require both total hip arthroplasty (THA) and lumbar spinal fusion (LSF), although there is a paucity of data regarding how the sequential timing of these procedures may influence clinical outcomes. This study aims to compare complications and spinopelvic parameters in patients with HSS who underwent either LSF first or THA first.

methodsA systematic search of PubMed and Scopus was conducted for randomized and nonrandomized studies investigating complications and spinopelvic parameters in patients with HSS who had undergone THA and LSF. The Methodological Index for Non-Randomized Studies (MINORS) tool was utilized to assess the risk of bias in included studies. Relevant outcomes were pooled for meta-analysis.

resultsEleven articles were included in this study. There was a significantly higher THA dislocation rate in patients who had undergone LSF first compared to those who had THA first (OR: 3.17, 95% CI 1.23-8.15, P = 0.02). No significant difference was found in terms of THA aseptic loosening (OR: 0.86; 95% CI 0.32-2.32, p = 0.77) and revision rate (OR: 1.18, 95% CI: 0.53-2.62) between these two groups. Individuals who received THA only showed a significantly lower risk of hip dislocation (OR: 0.14, 95% CI: 0.08-0.25, P < 0.00001) and THA revision (OR: 0.22, 95% CI: 0.14-0.36, P < 0.00001) compared to patients with a previous LSF.

conclusionsIn HSS patients who underwent both LSF and THA, those who received LSF first displayed an increased risk of hip dislocation after subsequent THA. Additionally, the relative risks of dislocation and revision rate appeared significantly lower in patients who had undergone THA only when compared to THA patients with a history of previous LSF. Due to the impact of LSF on spinopelvic biomechanics, caution must be exercised when performing THA in individuals with instrumented spines. PROSPERO ID: CRD42023412447. LEVEL OF EVIDENCE: LL.

Indexed as

Arthroplasty, Replacement, HipLumbar VertebraeSpinal FusionHip DislocationHip JointHumansPostoperative ComplicationsRisk FactorsSyndromeHip osteoarthritisHip-spine syndromeSpinal stenosisSpine fusionSpinopelvicTotal hip arthroplasty

Identifiers

PMID39272046
PMCPMC11395984

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.