Evidence map›Paper›PMID 39271797›Full record

ArticleSpinal cord2024

Self-reported benzodiazepine use among adults with chronic spinal cord injury in the southeastern USA: associations with demographic, injury, and opioid use characteristics.

Nicole D DiPiro, Clara E Dismuke-Greer, James S Krause

Abstract read
In one paragraph

Article in Spinal cord, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Nicole D DiPiroCollege of Health Professions, Medical University of South Carolina, Charleston, SC, USA. debarge@musc.edu.ORCID 0000-0003-1459-4690
Clara E Dismuke-GreerHealth Economics Resource Center, Veterans Affairs Palo Alto, Menlo Park, CA, USA.
James S KrauseCollege of Health Professions, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0001-8129-5389

Funding

ACL HHS 90DPHF0009
6 · The paper itself

Abstract

STUDY

designCross-sectional cohort study.

objectivesTo examine: (1) the self-reported frequency of specific prescription benzodiazepine use, (2) concurrent benzodiazepine and opioid use, and (3) sociodemographic, SCI, and opioid use factors associated with frequent benzodiazepine use.

settingCommunity.

methodsParticipants included 918 community dwelling adults with chronic ( > 1 year) traumatic SCI originally identified from a specialty hospital or a state-based surveillance system. Self-reported frequency of specific prescription benzodiazepines and opioids used, concurrent use, and factors associated with use were assessed.

resultsTwenty percent reported any benzodiazepine use in the past year and 13% reported at least weekly use. Concurrent daily or weekly use of benzodiazepines and opioids was reported by 6.5%, with those individuals taking an average of 1.1 (0.4) benzodiazepines and 1.4 (0.6) opioids. Compared to younger adults, those 50-65 years old had lower odds of at least weekly benzodiazepine use (OR = 0.50, 95% CI, 0.29-0.89, p-value = 0.02). Non-Hispanic Blacks reported lower use of benzodiazepines compared to non-Hispanic whites (OR = 0.32, 95% CI, 0.15-0.68, p-value = <0.01). Weekly opioid use was associated with higher odds of using benzodiazepines (OR = 3.10, 95%CI, 1.95-4.95, p-value = <0.01).

conclusionsBenzodiazepine use was commonly reported among those with SCI. Despite the potential risks, a high portion of those who reported benzodiazepine use also reported prescription opioid use. The findings highlight the need for monitoring of prescription medication use to avoid potentially risky concurrent use and adverse outcomes.

Indexed as

Analgesics, OpioidBenzodiazepinesSelf ReportSpinal Cord InjuriesAdultAgedChronic DiseaseCohort StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedSoutheastern United StatesYoung AdultAnalgesics, OpioidBenzodiazepines

Identifiers

PMID39271797
PMCPMC11549035

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.