ArticleNature communications2024
HIF-2α-dependent induction of miR-29a restrains T
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Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
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Who cites it
20 citing papers in PubMed.
- The role of hypoxia-inducible factors in myocardial ischaemia-reperfusion injury and cardioprotection.Nature reviews. Cardiology · 2026Review
- Selective Packaging of miR-22 and miR-29 Orthologues into Extracellular Vesicles of the Porcine Whipworm Trichuris Suis.Journal of extracellular vesicles · 2026Article
- Interplay between ischemia-reperfusion and metabolic reprogramming.Apoptosis : an international journal on programmed cell death · 2026Review
- Targeting SLK protects against cerebral ischemia-reperfusion injury by regulating USP8-mediated HIF-1α stabilization and RhoA/ROCK activation.Cellular & molecular biology letters · 2026Article
- GBP5 Aggravates Acute Lung Injury Via NLRP3 Inflammasome Activation While Inducing a HIF-1α-CD73-adenosine Feedback Loop.Inflammation · 2026Article
- MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review).International journal of molecular medicine · 2026Review
- Dysfunction of mitochondria in intestinal epithelial cells: a key player in the pathogenesis of inflammatory bowel diseases.Gastroenterology report · 2026Review
- MiR-29a deficiency disrupts gut microbiota-bile acid homeostasis and impairs the anti-inflammatory effects of lithocholic acid in colitis.Frontiers in cellular and infection microbiology · 2026Article
- Interplay Between Dysregulated Immune System and the Footprints of Blood-Borne miRNAs in Treatment Naive Crohn's Disease and Ulcerative Colitis Patients.International journal of molecular sciences · 2025Article
- Article
- Obesity-Driven Metabolic Disorders: The Interplay of Inflammation and Mitochondrial Dysfunction.International journal of molecular sciences · 2025Review
- Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Microglial metabolic reprogramming drives cognitive decline in heart failure with preserved ejection fraction.bioRxiv : the preprint server for biology · 2025Article
- Purinergic signaling modulates CD4+ T cells with cytotoxic potential during Trypanosoma cruzi infection.The Journal of clinical investigation · 2025Article
- Role of Hypoxia-Inducible Factors in Respiratory Syncytial Virus Infection-Associated Lung Disease.International journal of molecular sciences · 2025Article
- The epigenetic hallmarks of immune cells in cancer.Molecular cancer · 2025Review
- Recent insights and perspectives into the role of the miRNA‑29 family in innate immunity (Review).International journal of molecular medicine · 2025Review
- An optimised faecal microRNA sequencing pipeline reveals fibrosis in Trichuris muris infection.Nature communications · 2025Article
- Progressive Deactivation of Hydroxylases Controls Hypoxia-Inducible Factor-1α-Coordinated Cellular Adaptation to Graded Hypoxia.Research (Washington, D.C.) · 2025Article
- Hypoxia-inducible-factors differentially contribute to clinical disease and viral replication during RSV infection.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
22 authors.
Agnieszka K Czopik *Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA. Agnieszka.K.Czopik@uth.tmc.edu.ORCID 0009-0000-7179-7537
Eóin N McNamee *Mucosal Inflammation Program, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Victoria VaughnDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Xiangsheng HuangDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
In Hyuk BangDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Trent ClarkDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Yanyu WangDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Wei RuanDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0002-2718-7923
Tom NguyenMucosal Inflammation Program, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.ORCID 0000-0003-4222-4099
Joanne C MastersonMucosal Inflammation Program, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.ORCID 0000-0002-8336-9879
Eunyoung TakDigestive Health Institute, Children's Hospital Colorado, Aurora, CO, USA.
Sandra FrankOrgan Protection Program, Department of Anesthesiology, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-1749-0339
Colm B CollinsMucosal Inflammation Program, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Howard LiDivision of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado - Anschutz Medical Campus, Aurora, CO, USA.
Cristian Rodriguez-AguayoDepartmental of Experimental Therapeutics and Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-7880-7723
Gabriel Lopez-BeresteinDepartmental of Experimental Therapeutics and Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mark E GerichMucosal Inflammation Program, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Glenn T FurutaMucosal Inflammation Program, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Xiaoyi YuanDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0002-2898-6495
Anil K SoodDepartmental of Experimental Therapeutics and Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0003-4242-1762
Edwin F de ZoetenMucosal Inflammation Program, University of Colorado Anschutz School of Medicine, Aurora, CO, USA. Edwin.DeZoeten@childrenscolorado.org.ORCID 0000-0002-0946-9759
Holger K EltzschigDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0002-5676-6473
Funding
microRNA miR-147 Dampens Alveolar Epithelial Inflammation During ARDSR01HL154720 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K. · 2021 to 2024
$2.2MTargeting Myeloid Dependent MicroRNAs in Acute Respiratory Distress SyndromeR01HL155950 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Xiaoyi Yuan · 2022 to 2026
$2.0MTargeting MicroRNA miR-122 for the Treatment of Perioperative Liver InjuryR01DK122796 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K., JU, CYNTHIA · 2020 to 2023
$1.8MmicroRNA-dependent regulation of intestinal T-cells²R01DK111856 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DE ZOETEN, EDWIN FULCO · 2018 to 2022
$1.7MMicroRNA Shuttling during Acute Respiratory Distress SyndromeR01HL133900 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K. · 2017 to 2020
$1.5MNHLBI NIH HHS R01 HL133900NHLBI NIH HHS R01 HL154720NHLBI NIH HHS R01 HL155950NIDDK NIH HHS R01 DK111856NIDDK NIH HHS R01 DK122796United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs (CDMRP) HT94252310094
Abstract
Metabolic imbalance leading to inflammatory hypoxia and stabilization of hypoxia-inducible transcription factors (HIFs) is a hallmark of inflammatory bowel diseases. We hypothesize that HIF could be stabilized in CD4
Indexed as
Basic Helix-Loop-Helix ProteinsColitisMicroRNAsTh1 CellsAnimalsCD4-Positive T-LymphocytesDisease Models, AnimalEndothelial PAS Domain-Containing Protein 1FemaleHumansMaleMiceMice, Inbred C57BLMice, KnockoutT-bet Transcription FactorT-Box Domain ProteinsBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1MicroRNAsMIRN29 microRNA, mouseT-bet Transcription FactorT-Box Domain Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.