Evidence map›Paper›PMID 39271291›Full record

ArticleGenome research2024

Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of

Alicja Pacholewska, Matthias Lienhard, Mirko Brüggemann, Heike Hänel, Lorina Bilalli, Anja Königs, Felix Heß, Kerstin Becker, Karl Köhrer, Jesko Kaiser and 9 more

Abstract read
In one paragraph

Article in Genome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. bioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Facts and Hopes: Toward the Next Quantum Leap in Melanoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Alicja Pacholewska *Institute for Translational Epigenetics, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.ORCID 0000-0002-4888-4883
Matthias Lienhard *Department of Computational Molecular Biology, Max Planck Institute (MPI) for Molecular Genetics, 14195 Berlin, Germany.ORCID 0000-0002-2549-3142
Mirko Brüggemann *Buchmann Institute for Molecular Life Sciences and Institute of Molecular Biosciences, Goethe University Frankfurt, 60438 Frankfurt, Germany.
Heike HänelInstitute of Molecular Biology, 55128 Mainz, Germany.
Lorina BilalliInstitute for Translational Epigenetics, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.
Anja KönigsInstitute for Translational Epigenetics, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.
Felix HeßInstitute for Translational Epigenetics, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.
Kerstin BeckerGenomics and Transcriptomics Laboratory, Biological and Medical Research Center, Heinrich Heine University and West German Genome Center, 40225 Düsseldorf, Germany.
Karl KöhrerGenomics and Transcriptomics Laboratory, Biological and Medical Research Center, Heinrich Heine University and West German Genome Center, 40225 Düsseldorf, Germany.
Jesko KaiserInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Norbert GattermannDepartment of Hematology, Oncology, and Clinical Immunology, University Hospital Düsseldorf, 40225 Düsseldorf, Germany.
Michael HallekCenter for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.
Carmen D HerlingDepartment I of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Düsseldorf, University Hospital Cologne, 50937 Cologne, Germany.
Julian KönigInstitute of Molecular Biology, 55128 Mainz, Germany.
Christina Grimm *Institute for Translational Epigenetics, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.ORCID 0000-0002-4676-8870
Ralf Herwig *Department of Computational Molecular Biology, Max Planck Institute (MPI) for Molecular Genetics, 14195 Berlin, Germany.
Kathi Zarnack *Buchmann Institute for Molecular Life Sciences and Institute of Molecular Biosciences, Goethe University Frankfurt, 60438 Frankfurt, Germany.ORCID 0000-0003-3527-3378
Michal R Schweiger *Institute for Translational Epigenetics, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany; mschweig@uni-koeln.de.ORCID 0000-0002-4672-0623

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in splicing factor 3B subunit 1 (

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellMutationMyelodysplastic SyndromesPhosphoproteinsRNA Splicing FactorsTranscriptomeHumansMaleRNA Splice SitesRNA SplicingPhosphoproteinsRNA Splice SitesRNA Splicing FactorsSF3B1 protein, human

Identifiers

PMID39271291
PMCPMC11610591

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.