Evidence map›Paper›PMID 39271244›Full record

ArticleJournal of neurology, neurosurgery, and psychiatry2025

Imaging endolymphatic space of the inner ear in vestibular migraine.

Valerie Kirsch, Rainer Boegle, Johannes Gerb, Emilie Kierig, Birgit B Ertl-Wagner, Sandra Becker-Bense, Thomas Brandt, Marianne Dieterich

Abstract read
In one paragraph

Article in Journal of neurology, neurosurgery, and psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valerie Kirsch *German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University, Munich, Germany.ORCID 0000-0002-9397-436X
Rainer Boegle *German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University, Munich, Germany.
Johannes GerbGerman Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University, Munich, Germany.ORCID 0000-0002-5053-1462
Emilie KierigGerman Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University, Munich, Germany.ORCID 0009-0000-5443-4806
Birgit B Ertl-WagnerDepartment of Radiology, SickKids, Toronto, Ontario, Canada.
Sandra Becker-BenseGerman Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University, Munich, Germany.ORCID 0000-0001-9214-3583
Thomas BrandtGerman Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University, Munich, Germany.ORCID 0000-0002-0454-2371
Marianne DieterichGerman Center for Vertigo and Balance Disorders, Ludwig-Maximilians-University, Munich, Germany marianne.dieterich@med.uni-muenchen.de.ORCID 0000-0001-9903-9594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVestibular migraine (VM), the most frequent episodic vertigo, is difficult to distinguish from Ménière's disease (MD) because reliable biomarkers are missing. The classical proof of MD was an endolymphatic hydrops (EH). However, a few intravenous gadolinium-enhanced MRI studies of the inner ear (

methodsIn a prospective case-control study of 200 participants, 75 patients with VM (49 females; mean age 46 years) and 75 with MD (36 females; mean age 55 years), according to the Bárány and International Headache Society, and 50 age-matched participants with normal vestibulocochlear testing (HP), were enrolled. Analyses of

resultsEH was maximal in MD (80%), less in VM (32%) and minimal in HP (22%). EH was milder in VM (mean grade 0.3) compared with MD (mean grade 1.3). The intralabyrinthine distribution was preferably found in the vestibulum in VM, but mainly in the cochlea in MD. There was no interaural lateralisation of EH in VM but in the affected ear in MD. The grade of EH in the vestibulum was correlated in both conditions with the frequency and duration of the attacks.

conclusionThree features of the

Indexed as

Ear, InnerEndolymphatic HydropsMigraine DisordersAdultAgedCase-Control StudiesFemaleHumansMagnetic Resonance ImagingMaleMeniere DiseaseMiddle AgedProspective StudiesMRIVERTIGO

Identifiers

PMID39271244
PMCPMC12015079

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.