Evidence map›Paper›PMID 39271139›Full record

ArticleNano letters2024

Differentially Induced Autophagy by Engineered Nanomaterial Treatment Has an Impact on Cellular Homeostasis and Cytotoxicity.

Victor Alcolea-Rodriguez, Verónica I Dumit, Rico Ledwith, Raquel Portela, Miguel A Bañares, Andrea Haase

Abstract read
In one paragraph

Article in Nano letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Victor Alcolea-RodriguezDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin 10589, Germany.ORCID 0000-0002-2392-0817
Verónica I DumitDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin 10589, Germany.
Rico LedwithDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin 10589, Germany.
Raquel PortelaInstituto de Catálisis y Petroleoquímica, ICP-CSIC, C/Marie Curie 2, Campus Cantoblanco, 28049 Madrid, Spain.ORCID 0000-0002-1882-4759
Miguel A BañaresInstituto de Catálisis y Petroleoquímica, ICP-CSIC, C/Marie Curie 2, Campus Cantoblanco, 28049 Madrid, Spain.ORCID 0000-0003-3875-4468
Andrea HaaseDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin 10589, Germany.ORCID 0000-0002-5288-7876

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering the increasing production of engineered nanomaterials (ENMs), new approach methodologies (NAMs) are essential for safe-by-design approaches and risk assessment. Our aim was to enhance screening strategies with a focus on reactivity-triggered toxicities. We applied

Indexed as

AutophagyCell SurvivalHomeostasisNanostructuresA549 CellsCeriumCopperHumansSilicon DioxideTHP-1 CellsTitaniumZinc Oxideceric oxideCeriumCoppercupric oxideSilicon DioxideTitaniumtitanium dioxideZinc Oxideautophagyhomeostasisnanosafetyoxidative stressproteomicssurface reactivity

Identifiers

PMID39271139
PMCPMC11440646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.