Evidence map›Paper›PMID 39269599›Full record

ArticleBrain imaging and behavior2024

Insomnia and stress: the mediating roles of frontoparietal network.

Miao He, Yuan Li, Mengting Chen, Huiyun Li, Chunrong Liang, Yanli Chen, Chunyan Long, Yuting Yang, Jingyi Ye, Yu Mao and 2 more

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Article in Brain imaging and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Miao He *Department of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Yuan Li *Key Laboratory of Cognition and Personality of the Ministry of Education, Faculty of Psychology, Southwest University, Chongqing, China.
Mengting ChenDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Huiyun LiDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Chunrong LiangDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Yanli ChenDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Chunyan LongDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Yuting YangDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Jingyi YeDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Yu MaoKey Laboratory of Cognition and Personality of the Ministry of Education, Faculty of Psychology, Southwest University, Chongqing, China.
Yan WangDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China. 906682584@qq.com.
Ling LiDepartment of Medical Psychology, Daping Hospital, Army Medical University, Chongqing, 400042, China. connie1230@foxmail.com.

Funding

Military medicine pre-research project of Army Medical University 2019XYY24
6 · The paper itself

Abstract

Insomnia is a widespread health problem among adults, and it impairs cognitive control and emotional regulation functions. Stress and insomnia are positively correlated, and their vicious cycle has been widely reported. In this study, we explore the neural biomarkers of insomnia from the perspective of whole-brain functional connectivity and investigate the neural mechanisms underlying the association between stress and insomnia. The current study was conducted on a cross-sectional sample (N = 430). First, we investigated the correlation between perceived stress and insomnia. Second, we applied connectome-based predictive modeling (CPM) to determine the neuromarkers of insomnia. Finally, we explored the neural basis underlying the association between perceived stress and insomnia. A significant positive correlation was found between perceived stress and insomnia in the present research. Results of CPM revealed the following as the neural substrates supporting insomnia: the emotion regulation circuit involving repetitive negative thinking and the cognitive control circuit involving attention control. According to further results from mediation analysis, the frontoparietal network supporting cognitive emotion regulation is an important neural mechanism that maintains the correlation between stress and insomnia. The present study offers a profound insight into the alterations of brain activity related to insomnia, and it further investigates the neural underpinnings of the robust association between stress and insomnia. This study also opens new avenues for neural interventions to alleviate stress-related insomnia.

Indexed as

ConnectomeFrontal LobeMagnetic Resonance ImagingNeural PathwaysParietal LobeSleep Initiation and Maintenance DisordersStress, PsychologicalAdultBrainCross-Sectional StudiesEmotional RegulationFemaleHumansMaleNerve NetYoung AdultCognitive impairment circuitFrontoparietal networkInsomniaMaladaptive emotional regulationPerceived stress

Identifiers

PMID39269599

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.