Observational studyAmerican journal of respiratory and critical care medicine2025
Temporal Exploration of Chronic Obstructive Pulmonary Disease Phenotypes: Insights from the COPDGene and SPIROMICS Cohorts.
Abstract readMulticenter StudyObservational Study
In one paragraph
Observational study in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Identification of clinical phenotypes and development of a predictive model for rapid lung function decline in COPD patients.Annals of medicine · 2026Article
- Article
- The Evolving Landscape of COPD Typization.Medicina (Kaunas, Lithuania) · 2026Review
- Sociodemographic differences in clinical phenotypes among patients with COPD: a latent class analysis.BMJ open respiratory research · 2026Article
- Clinical and Functional Heterogeneity of COPD Phenotypes: A Multicenter Study from Turkey (DIPTUR Study).Medicina (Kaunas, Lithuania) · 2026Observational
- Determinants and Phenotypes of Poorly Controlled COPD Using the RADAR Score: A Cohort in Real-World Primary Care.Journal of clinical medicine · 2026Article
- Mitochondrial dysfunction and the regulatory cell death crosstalk network in chronic obstructive pulmonary disease: from oxidative stress mechanisms to targeted therapeutic strategies.Frontiers in immunology · 2026Review
- Quantitative CT-derived lobar inter-tapering as a candidate imaging feature associated with airway-predominant non-emphysematous COPD.Frontiers in medicine · 2026Article
- Trajectory-based identification of cognitive-performance phenotypes across adulthood from psychophysiological testing.Frontiers in aging neuroscience · 2026Article
- Deconstructing Therapeutic Failure with Inhaled Therapy in Hospitalized Patients: Phenotypes, Risk Profiles, and Clinical Inertia.Biomedicines · 2025Article
- Limitations of Linear Dimensional Reduction Methods in Chronic Obstructive Pulmonary Disease Phenotyping.American journal of respiratory and critical care medicine · 2025Article
- Reply to Takefuji: Limitations of Linear Dimensional Reduction Methods in Chronic Obstructive Pulmonary Disease Phenotyping.American journal of respiratory and critical care medicine · 2025Article
- Navigating the Progression of Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2025Article
- Quantitative CT and COPD: cluster analysis reveals five distinct subtypes with varying exacerbation risks.BMC pulmonary medicine · 2025Article
Corrections and comments
- Commented on by
Authors and funding
21 authors.
Alexander J BellDepartment of Radiology.ORCID 0000-0002-6151-0915
Sundaresh RamDepartment of Radiology.ORCID 0000-0003-1828-9722
Wassim W LabakiDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-3203-5537
Susan MurraySchool of Public Health, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4387-7673
Ella A KazerooniDepartment of Radiology.
Stefanie GalbanDepartment of Radiology.
Fernando J MartinezWeill Cornell Medical College, New York, New York.
Charles R HattImbio, Inc., Minneapolis, Minnesota.ORCID 0000-0001-7097-5434
Jennifer M WangDivision of Pulmonary and Critical Care Medicine, and.
Vladimir IvanovNovartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts.
Paul McGettiganNovartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts.
Edward KhokhlovichNovartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts.ORCID 0000-0002-7678-5372
Enrico MaiorinoChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-0159-4221
Rahul SuryadevaraChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-3182-0250
Adel BoueizChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0003-1638-8575
Peter J CastaldiChanning Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0001-9920-4713
Evgeny M MirkesSchool of Computing and Mathematical Sciences, University of Leicester, Leicester, United Kingdom.ORCID 0000-0003-1474-1734
Andrei ZinovyevIn Silico R&D, Evotec, Toulouse, France; and.ORCID 0000-0002-9517-7284
Alexander N GorbanSchool of Computing and Mathematical Sciences, University of Leicester, Leicester, United Kingdom.ORCID 0000-0001-6224-1430
Craig J GalbanDepartment of Radiology.ORCID 0000-0001-5596-7487
MeiLan K HanDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-9095-4419
Funding
Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1MSPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9M(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9MSPIROMICS GIC SupportU24HL141762 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J, O'NEAL, WANDA K · 2018 to 2022
$7.2MImaging and multi-omics analyses to identify molecular subtypes of distinct emphysema patternsR01HL167072 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Adel El Boueiz · 2023 to 2026
$3.4MPrediction of COPD Progression by PRMR01HL150023 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GALBAN, CRAIG J, HAN, MEILAN K · 2020 to 2023
$2.8MDefining Pathways in COPD Patient Oriented ResearchK24HL138188 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MeiLan K Han · 2017 to 2026
$1.2MLinking endotype and phenotype to understand COPD heterogeneity via deep learning and network scienceK01HL166705 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Enrico Maiorino · 2023 to 2026
$713kDefining Combined Pulmonary Fibrosis and Emphysema (CPFE) using Quantitative CT ImagingF32HL175973 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, JENNIFER MIN · 2024 to 2025
$174kAlpha-1 FoundationEngineering and Physical Sciences Research Council EP/V025295NHLBI NIH HHS F32 HL175973NHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900014CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268200900020CNHLBI NIH HHS K01 HL166705NHLBI NIH HHS K24 HL138188NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS R01 HL150023NHLBI NIH HHS R01 HL167072NHLBI NIH HHS U01 HL137880NHLBI NIH HHS U24 HL141762
Abstract
PubMed holds no abstract for this paper.
Indexed as
Pulmonary Disease, Chronic ObstructiveAgedCohort StudiesCross-Sectional StudiesDisease ProgressionFemaleHumansLongitudinal StudiesMaleMiddle AgedPhenotypeReproducibility of Resultsairway diseaseCOPDdisease progressionemphysemaphenotypes
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.