Evidence map›Paper›PMID 39269208›Full record

ArticleMicrobiology spectrum2024

Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum.

Ya-Pei Wang, Shu-Wen Yang, Fan Jia, Wei Wang, Xue Xu, Yi-Xuan Wang, Jing-Feng Bi, Bo-An Li

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ya-Pei Wang *Laboratory Department, Fifth Medical Center of PLA General Hospital, Beijing, China.
Shu-Wen Yang *Grade 2022 Postgraduate Class, School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, China.ORCID 0009-0004-0364-7819
Fan Jia *Laboratory Department, Fifth Medical Center of PLA General Hospital, Beijing, China.
Wei WangLaboratory Department, Fifth Medical Center of PLA General Hospital, Beijing, China.
Xue XuPhase I Clinical Trial Ward, Senior Department of Infectious Diseases Medicine, Fifth Medical Center of PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Yi-Xuan WangGrade 2022 Postgraduate Class, School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, China.
Jing-Feng BiPhase I Clinical Trial Ward, Senior Department of Infectious Diseases Medicine, Fifth Medical Center of PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.ORCID 0000-0002-4114-4372
Bo-An LiLaboratory Department, Fifth Medical Center of PLA General Hospital, Beijing, China.ORCID 0000-0003-1999-9398

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the influence of storage temperature and time on the stability of different concentrations of hepatitis C virus nucleic acid (HCV RNA) samples and to provide data reference for laboratory quality control. Serum samples of 10 patients with HCV RNA detection quantitation of 10 IMPORTANCE: Previously, there were few reports about the influence of different concentrations of sample nucleic acid on the stability of samples at various temperatures and times in various literatures. Therefore, it is necessary to analyze the influence of concentration factors on the stability of samples and test results at different storage times and temperatures. This study took the concentration of hepatitis C virus nucleic acid as the research object to further understand the stability of hepatitis C virus nucleic acid test samples under various storage conditions, to provide data reference for the treatment of hepatitis C virus nucleic acid and RNA test samples before clinical laboratory test, and provide guidance and help for the improvement of laboratory quality control.

Indexed as

HepacivirusHepatitis CRNA, ViralSpecimen HandlingTemperatureFemaleHumansMaleRNA StabilityTime FactorsRNA, Viralhepatitis C virus nucleic acidquality controlribonuclease

Identifiers

PMID39269208
PMCPMC11448131

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.