Recent Advances of Stretchable Nanomaterial-Based Hydrogels for Wearable Sensors and Electrophysiological Signals Monitoring.

Electrophysiological monitoring is a commonly used medical procedure designed to capture the electrical signals generated by the body and promptly identify any abnormal health conditions. Wearable sensors are of great significance in signal acquisition for electrophysiological monitoring. Traditional electrophysiological monitoring devices are often bulky and have many complex accessories and thus, are only suitable for limited application scenarios. Hydrogels optimized based on nanomaterials are lightweight with excellent stretchable and electrical properties, solving the problem of high-quality signal acquisition for wearable sensors. Therefore, the development of hydrogels based on nanomaterials brings tremendous potential for wearable physiological signal monitoring sensors. This review first introduces the latest advancement of hydrogels made from different nanomaterials, such as nanocarbon materials, nanometal materials, and two-dimensional transition metal compounds, in physiological signal monitoring sensors. Second, the versatile properties of these stretchable composite hydrogel sensors are reviewed. Then, their applications in various electrophysiological signal monitoring, such as electrocardiogram monitoring, electromyographic signal analysis, and electroencephalogram monitoring, are discussed. Finally, the current application status and future development prospects of nanomaterial-optimized hydrogels in wearable physiological signal monitoring sensors are summarized. We hope this review will inspire future development of wearable electrophysiological signal monitoring sensors using nanomaterial-based hydrogels.