Evidence map›Paper›PMID 39269036›Full record

ArticleJournal of clinical laboratory analysis2024

Evaluating the Association of Anthropometric Indices With Total Cholesterol in a Large Population Using Data Mining Algorithms.

Sahar Arab Yousefabadi, Somayeh Ghiasi Hafezi, Alireza Kooshki, Marzieh Hosseini, Amin Mansoori, Mark Ghamsary, Habibollah Esmaily, Majid Ghayour-Mobarhan

Abstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sahar Arab YousefabadiStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Somayeh Ghiasi HafeziDepartment of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
Alireza KooshkiStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Marzieh HosseiniDepartment of Biostatistics, College of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Amin MansooriDepartment of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
Mark GhamsarySchool of Public Health, Loma Linda University, Loma Linda, California, USA.
Habibollah EsmailyDepartment of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0003-4139-546X
Majid Ghayour-MobarhanDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0002-1081-6754

Funding

Mashhad University of Medical Science (MUMS), Mashhad, Iran 951214
6 · The paper itself

Abstract

backgroundUnbalanced levels of serum total cholesterol (TC) and its subgroups are called dyslipidemia. Several anthropometric indices have been developed to provide a more accurate assessment of body shape and the health risks associated with obesity. In this study, we used the random forest model (RF), decision tree (DT), and logistic regression (LR) to predict total cholesterol based on new anthropometric indices in a sex-stratified analysis.

methodOur sample size was 9639 people in which anthropometric parameters were measured for the participants and data regarding the demographic and laboratory data were obtained. Aiding the machine learning, DT, LR, and RF were drawn to build a measurement prediction model.

resultsAnthropometric and other related variables were compared between both TC <200 and TC ≥200 groups. In both males and females, Lipid Accumulation Product (LAP) had the greatest effect on the risk of TC increase. According to results of the RF model, LAP and Visceral Adiposity Index (VAI) were significant variables for men. VAI also had a stronger correlation with HDL-C and triglyceride. We identified specific anthropometric thresholds based on DT analysis that could be used to classify individuals at high or low risk of elevated TC levels. The RF model determined that the most important variables for both genders were VAI and LAP.

conclusionWe tend to present a picture of the Persian population's anthropometric factors and their association with TC level and possible risk factors. Various anthropometric indices indicated different predictive power for TC levels in the Persian population.

Indexed as

AnthropometryCholesterolData MiningAdultAgedAlgorithmsDecision TreesFemaleHumansMaleMiddle AgedCholesterolanthropometric indicesmachine learning methodspredictortotal cholesterol

Identifiers

PMID39269036
PMCPMC11484741

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.