SynthesisLiver international : official journal of the International Association for the Study of the Liver2024
Prevalence, trends, and distribution of hepatitis C virus among the general population in sub-Saharan Africa: A systematic review and meta-analysis.
Synthesis in Liver international : official journal of the International Association for the Study of the Liver, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prevalence of Hepatitis B Virus Infection in Cameroon: A Systematic Review and Meta-Analysis.Journal of viral hepatitis · 2026Pooled it
- Prevalence of hepatitis C viral infection in Ghana: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Risk Factors for Hepatitis C Virus Among the General Population in Sub-Saharan Africa-An Analysis of Systematic Review Data.Journal of viral hepatitis · 2025Pooled it
- Prevalence, trends, and distribution of hepatitis C virus among the general population in sub-Saharan Africa: A systematic review and meta-analysis.Liver international : official journal of the International Association for the Study of the Liver · 2024Pooled it
- Hepatitis B and C Prevention, Screening, and Diagnostic Services at HIV Treatment Sites: International Epidemiology Databases to Evaluate AIDS.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Immunological Determinants of Oncogenic Virus-Driven Cancers in Africa: Mechanisms, Co-Infections and Public Health Challenges.Pathogens (Basel, Switzerland) · 2026Review
- Prevalence and risk factors of hepatitis B, hepatitis C, and syphilis among reproductive-age adults in the Tigray region, Northern Ethiopia: a community-based cross-sectional study.Scientific reports · 2026Article
- Molecular diagnosis of HTLV-1 and HCV infection in polytransfused sickle cell disease in Kinshas: case of CMMASS.BMC infectious diseases · 2026Article
- Factors associated with chronic kidney disease among patients with hepatitis c infection attending Kigeme district hospital, Rwanda.Scientific reports · 2026Article
- Hepatitis C missed diagnostic opportunities: The role of reflex viral load testing in the era of direct acting antivirals, a descriptive South African study from 2017 to 2021.Southern African journal of infectious diseases · 2026Article
- Seroprevalence and Determinants of Hepatitis B and C Viral Infections Among Pregnant Women Attending Debark General Hospital, Northwest Ethiopia.BioMed research international · 2026Article
- A study protocol for co-designing risk communication strategies for hepatitis C virus (HCV) testing among priority populations in Johannesburg district, Gauteng, South Africa.Discover public health · 2026Article
- Comparison of Antibody Confirmation Assays for Hepatitis C Virus Testing in Patients With HIV.Sexually transmitted diseases · 2025Article
- Trends in the seroprevalence of hepatitis C viruses among patients received at the Centre Pasteur du Cameroun, with an indication of anti-HCV Ac serology from 2019 to 2024.BMC infectious diseases · 2025Article
- Revealing New Trends in the Global Burden of Hepatocellular Cancer Related to Hepatitis C Virus by Region, Sociodemographic Index, and Sex.Journal of clinical medicine · 2025Article
- Seroprevalence of hepatitis B, hepatitis C, and HIV in pregnant women attending a tertiary care hospital in Mogadishu, Somalia, 2017-2021.BMC infectious diseases · 2025Article
- Study on the effect of CeOScientific reports · 2025Article
- Seroprevalence of Hepatitis C in Ethiopia: First National Study Based on the 2016 Ethiopian Demographic and Health Survey.Journal of viral hepatitis · 2025Article
- Revealing viral hepatitis epidemiology in the Democratic Republic of Congo: insights from yellow fever surveillance reanalysis.Tropical medicine and health · 2025Article
- Elimination of HCV Infection: Recent Epidemiological Findings, Barriers, and Strategies for the Coming Years.Viruses · 2024Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
BACKGROUND AND
aimsAlthough the evidence is uncertain, existing estimates for hepatitis C virus (HCV) in sub-Saharan Africa (SSA) indicate a high burden. We estimated HCV seroprevalence and viraemic prevalence among the general population in SSA.
methodsWe searched Medline, Embase, Web of Science, APA PsycINFO, and World Health Organization Africa Index Medicus for community-based studies. Study quality was assessed using the Joanna Briggs Institute critical appraisal tool, and heterogeneity using the index of heterogeneity (I
resultsWe synthesized 130 studies. Overall, SSA HCV seroprevalence from the random-effects model was 4.17% (95% confidence interval [CI]: 3.71-4.66, I
conclusionsHCV seroprevalence in SSA remains high. Populations aged ≥65 years, rural communities, Africa-Western, and some countries in Africa-Central and Africa-Eastern appear disproportionately affected. These results underline the need for governmental commitment to achieve the 2030 global HCV elimination targets.
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