Evidence map›Paper›PMID 39268632›Full record

ReviewCNS neuroscience & therapeutics2024

Advanced progress of vestibular compensation in vestibular neural networks.

Jun Wang, Yuejin Zhang, Huajing Yang, E Tian, Zhaoqi Guo, Jingyu Chen, Caijuan Qiao, Hongqun Jiang, Jiaqi Guo, Zhanghong Zhou and 5 more

Abstract readReview
In one paragraph

Review in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Case report and literature review of subclavian steal syndrome presenting with otologic symptoms as the initial clinical manifestation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  4. Article
  5. Abnormal neural circuits and altered brain network topological properties in patients with chronic unilateral vestibulopathy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jun WangDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Yuejin ZhangDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Huajing YangDepartment of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
E TianDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhaoqi GuoDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jingyu ChenDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Caijuan QiaoDepartment of Physiology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China.
Hongqun JiangDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Jiaqi GuoDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhanghong ZhouDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qing LuoDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Shiyu ShiDepartment of Rehabilitation, Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hongyi YaoDepartment of Rehabilitation, Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yisheng LuDepartment of Physiology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-1616-7812
Sulin ZhangDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-3609-6804

Funding

Central Funds Guiding the Local Science and Technology Development 20221ZDG020066Hubei Provincial Key Research and Development Program 2023BCB027Key Clinical Specialty of Jiangxi Province 202382National Key Research and Development Program of China 2023YFC2508002National Key Research and Development Program of China 2023YFC2508005National Key Research and Development Program of China 2023YFC2508403National Natural Science Foundation of China 82171152National Natural Science Foundation of China 82371168
6 · The paper itself

Abstract

Vestibular compensation is the natural process of recovery that occurs with acute peripheral vestibular lesion. Here, we summarize the current understanding of the mechanisms underlying vestibular compensation, focusing on the role of the medial vestibular nucleus (MVN), the central hub of the vestibular system, and its associated neural networks. The disruption of neural activity balance between the bilateral MVNs underlies the vestibular symptoms after unilateral vestibular damage, and this balance disruption can be partially reversed by the mutual inhibitory projections between the bilateral MVNs, and their top-down regulation by other brain regions via different neurotransmitters. However, the detailed mechanism of how MVN is involved in vestibular compensation and regulated remains largely unknown. A deeper understanding of the vestibular neural network and the neurotransmitter systems involved in vestibular compensation holds promise for improving treatment outcomes and developing more effective interventions for vestibular disorders.

Indexed as

Nerve NetVestibular DiseasesVestibular NucleiAnimalsHumansVestibular SystemVestibule, Labyrinthcommissural inhibition systemmedial vestibular nucleineural networksneurotransmittersvestibular compensation

Identifiers

PMID39268632
PMCPMC11393560

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.