Common Risk Factors for CD4 Cell Count and Hemoglobin Level among Female Adult HIV-Positive Patients: A Retrospective Longitudinal Study.

Background: HIV is one of the most significant worldwide health concerns of the twenty-first century and a serious threat to human society. Hemoglobin level and CD4 cell count are two of the most important biomarkers of HIV progression and patient survival. The objective of this study was to identify common risk factors associated with CD4 cell count and hemoglobin level among adult female HIV-positive patients treated with ART at the University of Gondar Comprehensive Specialized Hospital, Ethiopia. Methods: The source of data in this study was secondary data conducted in the University of Gondar Comprehensive Specialized Hospital from September 2015 to March 2022 . Data exploration in this study was normal histogram plot, box plot, and Q-Q plot considered to gain some visions of the data related to CD4 cell count and hemoglobin level. A Bayesian joint model was used in this longitudinal data set to get a wide range of information about adult female HIV-patients. Results: The mean with a standard deviation of hematocrit (%), red blood cell (10 Conclusion: This study concluded that, the risk factors visit time, weight, secondary educators, tertiary educators, married patients, patients who disclosed their HIV status to family members were associated with high CD4 cell count and hemoglobin level. While, hematocrit, RBC, lymphocyte count, separated marital status, widowed marital status, and substance-addicted patients were associated with low CD4 cell count and hemoglobin level. The author recommended that FMOH or other health professionals, program planners, decision makers, project implementers, government, and nongovernmental organizations should be given special attention for adult female patinets to minimize the risk of HIV progression and improve their health status. The author also recommended that health staff should conduct health-related studies for patients to examine continuous checkups. Health professionals also should give more attention to types of ART medication to reduce the progression of disease when the patients come back again into the hospital. Finally, adult female HIV-positive patients should be given special attention based on these important factors to improve their CD4 cell count, hemoglobin level, and better health quality.