Evidence map›Paper›PMID 39268483›Full record

ArticleFrontiers in cellular and infection microbiology2024

Isolation and characterization of two novel bacteriophages against carbapenem-resistant

Abrar Senhaji-Kacha, Mireia Bernabéu-Gimeno, Pilar Domingo-Calap, John Jairo Aguilera-Correa, Mateo Seoane-Blanco, Sara Otaegi-Ugartemendia, Mark J van Raaij, Jaime Esteban, Meritxell García-Quintanilla

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  3. Review
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  5. Article
  6. Article
  7. Hypervirulent and Drug-ResistantInternational journal of general medicine · 2026
    Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abrar Senhaji-KachaDepartment of Clinical Microbiology, Health Research Institute or Instituto de Investigación Sanitaria (IIS)-Fundación Jiménez Díaz, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Mireia Bernabéu-GimenoInstitute of Biología Integrativa de Sistemas, Universitat de València-The Spanish National Research Council or Consejo Superior de Investigaciones Científicas (CSIC), Paterna, Spain.
Pilar Domingo-CalapInstitute of Biología Integrativa de Sistemas, Universitat de València-The Spanish National Research Council or Consejo Superior de Investigaciones Científicas (CSIC), Paterna, Spain.
John Jairo Aguilera-CorreaDepartment of Clinical Microbiology, Health Research Institute or Instituto de Investigación Sanitaria (IIS)-Fundación Jiménez Díaz, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Mateo Seoane-BlancoDepartment of Macromolecular Structure, Centro Nacional de Biotecnología-The Spanish National Research Council or Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain.
Sara Otaegi-UgartemendiaDepartment of Macromolecular Structure, Centro Nacional de Biotecnología-The Spanish National Research Council or Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain.
Mark J van RaaijDepartment of Macromolecular Structure, Centro Nacional de Biotecnología-The Spanish National Research Council or Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain.
Jaime EstebanDepartment of Clinical Microbiology, Health Research Institute or Instituto de Investigación Sanitaria (IIS)-Fundación Jiménez Díaz, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Meritxell García-QuintanillaDepartment of Clinical Microbiology, Health Research Institute or Instituto de Investigación Sanitaria (IIS)-Fundación Jiménez Díaz, Universidad Autónoma de Madrid (UAM), Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase of antibiotic-resistant bacteria has become a global health emergency and the need to explore alternative therapeutic options arises. Phage therapy uses bacteriophages to target specific bacterial strains. Phages are highly specific and can target resistant bacteria. Currently, research in this regard is focused on ensuring reliability and safety to bring this tool into clinical practice. The first step is to conduct comprehensive preclinical research. In this work, we present two novel bacteriophages vB_Kpn_F13 and vB_Kpn_F14 isolated against clinical carbapenem-resistant

Indexed as

BacteriophagesBiofilmsCarbapenem-Resistant EnterobacteriaceaeCarbapenemsKlebsiella InfectionsKlebsiella pneumoniaePhage TherapyAnti-Bacterial AgentsGenome, ViralHost SpecificityHumansMicrobial Sensitivity TestsSewageAnti-Bacterial AgentsCarbapenemsSewagealternative therapybacteriophagesKlebsiella pneumoniaemultidrug-resistant (MDR)phage therapy

Identifiers

PMID39268483
PMCPMC11390652

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.