Evidence map›Paper›PMID 39268163›Full record

ArticleOncology letters2024

SCGB1A1 as a novel biomarker and promising therapeutic target for the management of HNSCC.

Jing Wang, Qianqian Xu, Jiangbo Yu, Aotian Xu, Lizheng Yu, Zhenggang Chen, Yang Cao, Rongtao Yuan, Zhongjie Yu

Abstract read
In one paragraph

Article in Oncology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jing WangCenter of Oral Medicine, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China.
Qianqian XuQingdao Cancer Institute, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, Shandong 266000, P.R. China.
Jiangbo YuCenter of Oral Medicine, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China.
Aotian XuR&D, Qingdao Sino-cell Biomedicine Co., Ltd., Qingdao, Shandong 266000, P.R. China.
Lizheng YuDepartment of Vascular Surgery, Qingdao Medical College, Qingdao University, Qingdao, Shandong 266000, P.R. China.
Zhenggang ChenCenter of Oral Medicine, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China.
Yang CaoCenter of Oral Medicine, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China.
Rongtao YuanCenter of Oral Medicine, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China.
Zhongjie YuR&D, Qingdao Sino-cell Biomedicine Co., Ltd., Qingdao, Shandong 266000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer (HNC) is the sixth most common type of cancer worldwide, and head and neck squamous cell carcinoma (HNSCC) accounts for 90% of HNC cases. Furthermore, HNSCC accounts for 400,000 cancer-associated deaths worldwide each year. However, at present there is an absence of a versatile biomarker that can be used for diagnosis, prognosis evaluation and as a therapeutic target for HNSCC. In the present study, bioinformatics analysis was used to assess the relationship between hub genes and the clinical features of patients with HNSCC. The findings from the bioinformatics analysis were then verified using clinical samples and

Indexed as

bioinformatics analysishead and neck squamous cell carcinomaSCGB1A1tumor immunologytumor metabolism

Identifiers

PMID39268163
PMCPMC11391500

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.