Evidence map›Paper›PMID 39268146›Full record

ArticleJournal of thoracic disease2024

Efficacy and tolerability of osimertinib with dabrafenib and trametinib in

Kevin Lu, Victoria Tse, Ghaith Altaie, Hatim Husain

Abstract readCase Reports
In one paragraph

Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Circular RNAJournal of thoracic disease · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kevin LuDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID https://orcid.org/0009-0004-4793-9928
Victoria TseDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Ghaith AltaieDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Hatim HusainDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acquired mutations within bypass pathways including Case Description: We retrospectively reviewed our clinical patient cohort at the University of California San Diego and patients from published case studies. Individuals who had metastatic Conclusions: We concluded that the addition of combination dabrafenib and trametinib can be tolerable and effective in patients with acquired

Indexed as

BRAF V600Ecase seriesdabrafenibEGFRNon-small cell lung cancer (NSCLC)trametinib

Identifiers

PMID39268146
PMCPMC11388243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.